Artery Research

+ Advanced search
2994 articles
Conference Abstract

P168 FEASIBILITY STUDY OF LOCAL PULSE WAVE VELOCITY ESTIMATION IN THE CAROTID ARTERY WITH MULTI-BEAM LASER DOPPLER VIBROMETER

Daniela Tommasin, Yanlu Li, Jonathan Reeves, Roel Baets, Steve Greenwald, Patrick Segers
Pages: 129 - 130
Background: An innovative device using Laser Doppler Vibrometry (LDV) has been designed [1] to measure the transit time of the pulse wave between two locations along the course of the carotid artery (CA) from skin surface vibrations for assessment of local pulse wave velocity (PWV) [2]. Aim: Tests were...
Conference Abstract

P3.11 ETHNIC DIFFERENCES IN ARTERIAL WAVEFORM MEASURES IN A LARGE SAMPLE OF ADULTS ENROLLED IN THE VITAMIN D ASSESSMENT (VIDA) STUDY

J. Sluyter, A. Hughes, S. Thom, K. Parker, A. Lowe, R. Scragg
Pages: 129 - 130
Few studies have examined whether central arterial wavTable:eform measures vary with ethnicity. We aimed to provide a more comprehensive examination of ethnic differences in several cardiovascular risk factors, which may reveal new ethnic variations. A cross-sectional (baseline) analysis of 5110 adults...
Conference Abstract

P169 RELATIONSHIP BETWEEN COMMON CAROTID DISTENSIBILITY/AORTIC STIFFNESS AND LEFT VENTRICULAR MORPHOLOGY AND FUNCTION IN RHEUMATOLOGIC PATIENTS

Michele Bevilacqua, Andrea Dalbeni, Angela Tagetti, Luca Gomarasca, Giovanni Orsolini, Andrea Giollo, Maurizio Rossini, Ombretta Viapiana, Giovanni Cioffi, Pietro Minuz, Cristiano Fava
Pages: 130 - 130
Introduction: Arterial stiffness is known to be associated with atherosclerosis, cardiac remodelling and cardiovascular diseases. In recent studies, common carotid artery rigidity was seen to better predict cardiac morphology and function if compared to aortic parameters. The aim of the study was to...
Conference Abstract

P3.12 PULSE WAVE VELOCITY AND DIABETES DURATION IN TYPE 2 DIABETES MELLITUS

D. Agnoletti, S. Millasseau, A. Salah-Mansour, A.D. Protogerou, Y. Zhang, C. Borghi, J. Blacher, M. Safar
Pages: 130 - 130
Type 2 diabetes mellitus (T2DM) duration is related to early vascular aging and diabetic complications. Aortic stiffness is considered an integrated marker of the combined effect of cardiovascular risk factors, and could represent one of the links between diabetes and cardiovascular disease. To our knowledge,...
Conference Abstract

P170 A FOREHEAD AND NASAL BRIDGE PULSE OXIMETER COMPARISON MEASUREMENTS ON HEALTHY SUBJECTS

Matti Huotari, Juha Röning, Kari Määttä
Pages: 130 - 130
Photoplethysmography (PPG) is a biophotonic technique which measures blood volume variations in vascular bed and it is well known for its utilization in pulse oximetry for the estimation of arterial blood oxygen saturation. Moving particles within the tissue bed generate rapidly changing absorption caused...
Conference Abstract

P3.13 ASSOCIATIONS OF CENTRAL AND PERIPHERAL PULSE PRESSURE WITH HEART STRUCTURE, SYSTOLIC AND DIASTOLIC FUNCTION IN ADOLESCENCE: FINDINGS FROM A GENERAL POPULATION COHORT

D.L. Santos Ferreira, A. Fraser, L.D. Howe, S. Jones, R. Tapp, D.A. Lawlor, A. Ness, G.D. Smith, N. Chaturvedi, A.D. Hughes
Pages: 130 - 130
Background: In adults central blood pressure has stronger associations with cardiovascular outcomes than peripheral blood pressure, with some evidence that this difference is greater in mid- than older-aged adults. The relationship of central blood pressure to cardiovascular structure and function in...
Conference Abstract

P171 CARDIOVASCULAR RISK EVALUATION IN BEHCET’S PATIENTS – THE ROLE OF CHRONIC INFLAMMATION IN ARTERIAL STIFFNESS

Maria Guimarães, Glória Alves, Cristina Cunha, Marta Cunha
Pages: 130 - 132
Introduction: Behcet’s disease (BD) is a chronic inflammatory syndrome with systemic manifestations. Systemic vasculitis contribute to vascular aging, increasing the arterial stiffness that can be inferred from the Pulse Wave Velocity (PWV) measurement. Carotid ultrasound evaluation allows vascular wall...
Conference Abstract

P3.15 ARTERIAL STIFFNESS IN NON-HYPERTENSIVE GHANAIAN SUBJECTS WITH TYPE 2 DIABETES

K. Yeboah, A.G.B. Amoah, D.A. Antwi, B. Gyan, V. Govoni, J.K. Cruickshank
Pages: 130 - 130
Background: Limited data exists on arterial stiffness in sub-Sahara Africa where diabetes and cardiovascular diseases are increasing rapidly. We aimed to compare the indices of arterial stiffness among type 2 diabetes (T2DM) and non-diabetes subjects (NDM), without hypertension, in Ghana. Method: Thirty...
Conference Abstract

P3.16 CARDIO ANKLE VASCULAR INDEX (CAVI) IS AN INDEPENDENT PREDICTOR OF CARDIOVASCULAR EVENTS IN 1000 PATIENTS

Satoh Yuta, Nagayama Daiji, Imamura Haruki, Ban Noriko, Kawana Hidetoshi, Nagumo Ayako, Yamaguchi Takashi, Ohira Masahiro, Saiki Atsuto, Shirai Kohji, Tatsuno Ichiro
Pages: 130 - 131
Objects: Recently, a novel arterial stiffness parameter called cardio-ankle vascular index (CAVI) has been developed. This study was conducted in order to elucidate the predictive value of CAVI for future cardiovascular events in 1000 persons. Subjects and methods: A total of 1,000 outpatients (513...
Research Article

Association between Life Stressors and Arterial Stiffness: The Finnish Retirement and Aging Study

Saana Karelius, Jussi Vahtera, Olli J. Heinonen, Teemu J. Niiranen, Sari Stenholm
Pages: 129 - 134
Objective: Besides traditional risk factors, other factors such as life stressors are linked with incident cardiovascular disease. However, the underlying mechanisms for this association remain mostly unknown. We studied the relation of life stressors (job strain, sleep loss due to worry, illness or...
Conference Abstract

P3.17 EFFECT OF HYPERTENSION ON ARTERIAL STIFFNESS IN GHANAIAN SUBJECTS WITH TYPE 2 DIABETES

K. Yeboah, D.A. Antwi, B. Gyan, V. Govoni, J.K. Cruickshank, A.G.B. Amoah
Pages: 131 - 131
Background: Hypertension exacerbates cardiovascular disease in type 2 diabetes (T2DM) but the ACCORD trial suggested limited impact on CVS events by hypertensive treatment. Our hypothesis is that arterial stiffness, measured as aortic pulse wave velocity (PWV) may underlie these events. Few data exist...
Conference Abstract

P3.18 ENDOTHELIAL FUNCTION BUT NOT IN INTIMA-MEDIA THICKNESS RELATES TO RENIN STATUS IN A MULTI-ETHNIC GROUP OF YOUNG HEALTHY ADULTS

K. Connell, J.K. Cruickshank, P. Chowienczyk
Pages: 131 - 131
Subjects of African and African-Caribbean ethnicity have been reported to have lower plasma renin activity (PRA), decreased endothelium-dependent vasomotor function and increased intima-media thickening relative to white European subjects. We explored whether vascular structure and function might be...
Conference Abstract

P1.9 EVALUATION OF AFFECTIVE TEMPERAMENTS AND ARTERIAL STIFFNESS IN TREATED HYPERTENSIVE PATIENTS

J. Nemcsik, A. László, L. Babos, Z. Kis-Igari, A. Pálfy, P. Torzsa, A. Eőry, L. Kalabay, O. Cseprekál, A. Tislér, X. Gonda, Z. Rihmer
Pages: 131 - 131
Conference Abstract

P3.19 AORTIC PULSE PRESSURE BETTER PREDICTS INCREASES ARTERIAL STIFFNESS COMPARED TO BRACHIAL AND AMBULATORY MEASUREMENTS

D. Terentes-Printzios, C. Vlachopoulos, N. Ioakeimidis, K. Aznaouridis, P. Pietri, M. Abdelrassoul, P. Xaplanteris, A. Aggelakas, C. Stefanadis
Pages: 131 - 131
Objectives: Hypertension is associated with increased arterial stiffness, which is an independent predictor of cardiovascular risk. Aortic systolic blood pressure (SBP) and/or pulse pressure (PP) better predicts cardiovascular events than peripheral blood pressure. The present study compared the discriminative...
Conference Abstract

P3.20 CLINICAL SIGNIFICANCE OF AMBULATORY ARTERIAL STIFFNESS INDEX (AASI) IN YOUNG STAGE 1 HYPERTENSIVE’ S

F. Saladini, E. Benetti, C. Fania, L. Mos, P. Ballerini, E. Cozzutti, G. Garavelli, S. Cozzio, E. Casiglia, P. Palatini
Pages: 131 - 132
Objective: The aim of the study was to examine the relationship between AASI and age in a cohort of stage I hypertensives < 50 years of age and to investigate its predictive capacity for future established hypertension. Methods: We studied 1157 subjects from the HARVEST study (mean follow-up 5.9...
Mini Review

ADVANCES IN ARTERIAL STIFFNESS ASSESSMENT

Evelien Hermeling, Robert S. Reneman, Arnold P.G. Hoeks, Koen D. Reesink
Pages: 130 - 136
Although the clinical relevance of arterial stiffness is increasingly recognized, the applicability of arterial stiffness for individual cardiovascular risk assessment is hampered due to technical and physiological difficulties. Arterial stiffness is not constant with blood pressure and not constant...
Research Article

Effects of transient change in carotid arterial stiffness on arterial baroreflex during mild orthostatic stimulation

Jun Sugawara, Christopher K. Willie, Taiki Miyazawa, Hidehiko Komine, Philip N. Ainsle, Shigehiko Ogoh
Pages: 130 - 135
Stiffening of central conduit arteries –areas where the mechanoreceptors are embedded (e.g., ascending aorta and carotid artery) – is considered to be associated with the impaired baroreflex control in response to hypotensive stress. Arterial stiffness is modulated by vascular tone transiently and dynamically,...
Review Article

Accurate Measurement of Blood Pressure

Dean S. Picone
Pages: 130 - 136
Accurate Blood Pressure (BP) measurement is vital for appropriate diagnosis and management of cardiovascular risk. However, questions remain on the accuracy of cuff BP compared with invasive (intra-arterial) BP. Moreover, the critical physiological factors that are associated with inaccuracy of cuff...
Conference Abstract

P1.11 ARTERIAL STIFFNESS AND LEFT VENTRICULAR DIASTOLIC FUNCTION IN TREATED AND UNTREATED HYPERTENSIVES

W. Wojciechowska, K. Stolarz-Skrzypek, A. Olszanecka, L. Klima, J. Gasowski, T. Grodzicki, D. Czarnecka
Pages: 132 - 132
Conference Abstract

P172 ROLE OF ADIPOSE TISSUE AND SKELETAL MUSCLE IN MACROVASCULAR ATHEROSCLEROTIC OCCLUSIVE DISEASE-PERIPHERAL ARTERIAL DISEASE AND CAROTID ARTERY DISEASE

Joana Ferreira
Pages: 132 - 132
Purpose/Background/Objective: Carotid artery disease (CAD) and peripheral arterial disease (PAD) are non-cardiac manifestations of atherosclerotic disease, which are less extensively studied. Presently, adipose tissue (AT) and skeletal muscle (SM) are considered endocrine organs, producing cytokines...
Conference Abstract

P3.21 CENTRAL HEMODYNAMICS PARAMETERS IN BLACK HYPERTENSIVE PATIENTS BORN AND LIVING IN SUB-SAHARAN AFRICA

M.K. Kamdem, E.A. Birinus, D. Lemougoum, B.C. Anisiuba, J. Kaptue, J. Staessen, M’buyamba Rene, A. Odili
Pages: 132 - 132
Background: Few studies assessed arterial stiffness in Black hypertensive patients Born and living in sub-Saharan Africa, where cardiovascular disease reaches epidemic proportions. Methods: The Newer versus Older Antihypertensive Agents in African Hypertensive Patients (NOAAH) trial had recruited native...
Conference Abstract

P3.22 CHROMOSOME 9P21 LOCUS AND CORONARY ARTERY DISEASE – COLLABORATIVE META-ANALYSIS ON ANGIOGRAPHIC BURDEN AND MOLECULAR FUNCTION ANALYSIS

K. Chan, A. Motterle, R.S. Patel, X. Pu, S. Ye
Pages: 132 - 132
Objective: Chromosome 9p21 variants showed robust association with coronary heart disease in genome-wide association studies, but questions remain on the mechanism. We investigated the relationship of 9p21 locus with (1) angiographic coronary artery disease (CAD) burden and progression to myocardial...
Conference Abstract

P3.23 URINARY ALBUMIN EXCRETION FROM SPOT URINE SAMPLES PREDICT ALL-CAUSE AND STROKE MORTALITY IN AFRICANS

R. Schutte, A.E. Schutte, H.W. Huisman, J.M. van Rooyen, C.M.T. Fourie, R. Kruger, C.M.C. Mels, L. Malan, N.T. Malan, W. Smith, M. Greeff, A. Kruger
Pages: 132 - 133
Twenty-four hour urinary albumin excretion reflects general endothelial damage, relates to arterial stiffness, and predicts adverse health outcomes. Albumin determined from easily collected spot urine samples is also predictive. No prognostic evidence for albumin excretion from any means of urine collection...
Research Article

Analysis of Vascular Aging in Arterial Hypertension – Population-based Study: Preliminary Results

Juan Jailson Oliveira Almeida Costa, Roberta de Castro Araújo Cunha, Antonio de Assis Oliveira Alves Filho, Larissa Ribeiro Bessa, Rodrigo Lins Sant’Ana de Lima, Alana dos Reis Silva, Brenno Araújo e Souza, Catarina de Almeida Viterbo, Mariana Barreto Requião, Daniele Brustolim, Diorlene Oliveira da Silva, Lucélia Batista Neves Cunha Magalhães, Cecília Freitas da Silva Araújo
Pages: 131 - 138
Background: Arterial Hypertension (AH) is an uncertain and complex physiopathological disease with the Arterial Stiffness (AS) as one of the main cardiovascular alterations. Pulse Wave Velocity (PWV) is the gold standard marker for assessment of the vascular aging and an important predictor of cardiovascular...
Mini Review

Effects of drugs on cardiac and vascular function

Nicola De Luca, Claudia S. Cimmino, Salvatore Crispo
Pages: 131 - 133
Conference Abstract

P2.1 CAROTID PLAQUE MICROVASCULATURE ASSESSED USING DYNAMIC CONTRAST-ENHANCED MRI: COMPARING DIFFERENT REGIONS OF THE VASCULAR WALL

R. Van Hoof, E. Hermeling, N. Wijnen, F. Schreuder, M. Truijman, S. Voo, J. Cleutjens, J. Sluimer, S. Heeneman, R. Oostenbrugge, J.-W. Daemen, M. Daemen, J. Wildberger, M. Kooi
Pages: 133 - 133
Conference Abstract

P3.24 SEX-SPECIFIC ASSOCIATIONS BETWEEN CAROTID DISTENSIBILITY AND PRIOR BLOOD PRESSURE CATEGORIES – RESULTS FROM THE SAPALDIA COHORT

S. Caviezel, J. Dratva, E. Schaffner, C. Schindler, E. Zemp Stutz, N. Künzli, J.-M. Gaspoz, T. Rochat, N. Probst-Hensch, A. Schmidt-Trucksäss
Pages: 133 - 133
Objective: Hypertension is a major risk factor of cardiovascular events. To identify potential sex specific differences in the association of prior blood pressure (BP) to arterial stiffness, we studies the relative change of lumen diameter for a given pulse pressure (distensibility) in participants of...
Conference Abstract

P2.2 ULTRASOUND SPECKLE TRACKING HELPS IDENTIFY VULNERABLE CAROTID PLAQUES

A. Kaloshina, O. Kerbikov, E. Borskaya, S. Voynov, T. Krutova, A. Averyanov
Pages: 133 - 133
Conference Abstract

P3.25 THE EFFECT OF DIASTOLIC ASYMPTOTIC PRESSURE ON THE RESERVOIR PRESSURE IN HUMAN

A. Borlotti, S. Vermeersch, E.R. Rietzschel, P. Segers, A.W. Khir
Pages: 133 - 133
Background: Arterial diastolic asymptotic pressure (P∞) is the pressure reached when the heart stops beating. Determination of the reservoir pressure (Pr) requires a value of P∞ which was previously assumed (1), calculated (2) and measured (3, 4) as 0, 35, 14, 24 mmHg respectively. The effects of varying...
Conference Abstract

P3.26 ARTERIAL DISPENSABILITY IN STAGE 1 HYPERTENSION: COMPARISON BETWEEN PREMENOPAUSAL WOMEN AND MEN OF THE SAME AGE

F. Saladini, E. Benetti, L. Mos, A. Mazzer, A. De Pellegrin, P. Palatini
Pages: 133 - 133
Objective: To investigate whether arterial distensibility in hypertensive premenopausal women differs from that observed in men and whether these differences may vary according to age. Methods: We studied 385 young stage 1 hypertensives from the HARVEST study. Arterial distensibility predictors were...
Conference Abstract

P2.4 FEASIBILITY OF AORTIC ARCH MECHANICS - A STUDY IN NORMAL SUBJECTS

R. Teixeira, T. Pereira, R. Monteiro, A. Xarepe, M. Graca, J. Garcia, M. Ribeiro, N. Cardim, L. Gonçalves
Pages: 133 - 134
Conference Abstract

P3.27 ASSOCIATION STUDY OF APOE POLYMORPHISMS WITH ESSENTIAL HYPERTENSION IN BULGARIAN PATIENTS

R. Tzveova, T. Yaneva, Y. Matrozova, S. Vandeva, G. Naydenova, D. Pendicheva, R. Tarnovska, R. Kaneva, G. Nachev, V. Mitev
Pages: 133 - 134
Apolipoprotein E (ApoE) polymorphism influences lipid metabolism, but its association with essential hypertension (EH) is controversial. The objective of this study was to examine the association between ApoE polymorphisms and EH in Bulgarian population. We carried out a case-control association study...
Research Article

New insights into cardiovascular risk from the exercise central waveform

James E. Sharman
Pages: 132 - 137
Numerous studies in healthy individuals with normal office blood pressure (BP) have shown that a hypertensive response to exercise predicts the future onset of hypertension, as well as cardiovascular morbidity and mortality, independent of office BP. The mechanisms underlying the predictive value of...
Conference Abstract

P3.28 CENTRAL VS. PERIPHERAL AND STEADY VS. PULSATILE BLOOD PRESSURE COMPONENTS AS DETERMINANTS OF RETINAL MICRO-VESSEL DIAMETERS

Y.-M. Gu, Y.-P. Liu, T. Kuznetsova, F.-F. Wei, H. Struijker-Boudier, J.A. Staessen
Pages: 134 - 134
Objective: We assessed association of retinal micro-vessel diameter with central and peripheral BP. Methods: We post-processed retinal photographs taken in 514 subjects randomly selected from a Flemish population (mean age, 50.6 years; 50.8% women), using IVAN software to generate retinal arteriolar...
Conference Abstract

P3.29 ASSESSMENT OF THE DETERMINANTS OF LOCAL CAROTID STIFFNESS IN A GENERAL POPULATION IN NORTHERN ITALY

C. Aggiusti, A. Paini, M. Salvetti, F. Bertacchini, D. Stassaldi, C. Agabiti Rosei, G. Maruelli, G. Rubagotti, E. Agabiti Rosei, M.L. Muiesan
Pages: 134 - 134
Background: The determinants of aortic stiffness have been elucidated in several studies, while few data are available for carotid stiffness. Aim of the study was to identify the main determinants of carotid arterial stiffness parameters in a general population in Northern-Italy(Vobarno Study). Methods:183subjects(61%...
Conference Abstract

P3.30 DIFFERENCE IN THE PREVALENCE OF HYPERTENSION USING STANDARD BLOOD PRESSURE MEASUREMENT COMPARED TO AMBULATORY BLOOD PRESSURE MONITORING IN KILIFI, KENYA

A.O. Etyang, B. Warne, S. Kapesa, J.K. Cruickshank, L. Smeeth, J.A.G. Scott
Pages: 134 - 135
Background: As sub Saharan Africa (sSA) goes through demographic and epidemiological transition, accurate data on disease prevalence are required to guide allocation of scarce health resources between declining but still important infectious disease and emerging chronic conditions such as hypertension....
Conference Abstract

P2.10 ASSESSMENT OF CAROTID PULSE WAVE VELOCITY BY ULTRASOUND: A WAVE INTENSITY ANALYSIS-BASED APPROACH

N. Lascio, R. Bruno, F. Stea, V. Gemignani, E. Bianchini, L. Ghiadoni, F. Faita
Pages: 135 - 135
Conference Abstract

P3.31 CORRELATION OF CENTRAL HAEMODYNAMICS WITH HEALTH-RELATED QUALITY OF LIFE

D.A. Vrachatis, A. Argyris, A. Papadopoulos, T.G. Papaioannou, E. Aissopou, G. Konstantonis, D. Niakas, P. Sfikakis, A. Protogerou
Pages: 135 - 135
Objectives: High blood pressure (BP) levels have been reported to have an inverse association with the health-related quality of life (HRQOL). Moreover, the value of central beyond peripheral haemodynamics has been illustrated by a series of studies. We sought to investigate potential correlations between...
Conference Abstract

P3.32 THE NUMBER OF METABOLIC SYNDROME RISK FACTORS CORRELATES WITH AORTIC STIFFNESS

Vágovičová Petra, Mlíková Seidlerová Jitka, Filipovský Jan, Mayer Otto, Wohlfahrt Peter, Cífková Renata
Pages: 135 - 135
Objectives: Metabolic syndrome (MS) is a cluster of ≥3 risk factors (RF). The presence of subclinical organ damage increases the risk of cardiovascular disease in patients with MS. Arterial stiffness and wave reflections are independent predictors of cardiovascular disease. The aim of our study was to...
Conference Abstract

P4.01 PLASMA FIBULIN-1 IS INCREASED IN PATIENTS WITH ABDOMINAL AORTIC ANEURYSM BUT NOT PERIPHERAL ATHEROSCLEROTIC DISEASE

M.L. Hansen, M.D. Thomsen, J.S. Lindholt, L.M. Rasmussen
Pages: 135 - 135
Objectives: Fibulin-1 is an extracellular matrix protein that is increased in the arterial wall in diabetes. It is also present in plasma, where it is positively related to blood pressure and predicts mortality. In addition, plasma levels are associated with heart stiffness indices. The aim of this study...
Mini Review

Adducin and its relation to cardiovascular system

Jitka Seidlerová
Pages: 134 - 137
Adducin is a cytoskleton protein, which functions within the cells as a heterodimer composed of a combination of three subunits, α, β and γ. Each of these subunits is coded by genes (ADD1, ADD2, ADD3) mapping to different chromosomes. Mutation in ADD1 Gly460Trp polymorphism is associated with increased...
Conference Abstract

P2.14 ESTIMATION OF AORTIC ARCH PULSE WAVE VELOCITY IN MRI USING COMPLEX WAVELET CROSS-SPECTRUM

I. Bargiotas, A. Redheuil, E. Bollache, G. Soulat, A. Cesare, E. Mousseaux, N. Kachenoura
Pages: 136 - 136
Conference Abstract

P4.02 BASELINE CRP BUT NOT NSAID-USE PREDICTS FUTURE INCREASED ARTERIAL STIFFNESS IN ANKYLOSING SPONDYLITIS: RESULTS AFTER 5-YEAR FOLLOW UP

I.J. Berg, A.G. Semb, D. van der Heijde, T.K. Kvien, H. Dagfinrud, S.A. Provan
Pages: 136 - 136
Objective: Patients with ankylosing spondylitis (AS) have an increased risk of CVD, but previous studies have not shown a worsened risk profile regarding traditional cardiovascular risk factors. The objective was to investigate whether baseline CRP predicts future increased central arterial stiffness. Methods:...
Conference Abstract

P2.15 IDENTIFICATION OF FRAMEWORK CONDITIONS IN CUFF BASED BLOOD MEASUREMENT SYSTEMS

R. Lurf, M. Michael, C. Mayer, B. Hametner, T. Weber, S. Wassertheurer
Pages: 136 - 136
Conference Abstract

P4.03 APOPTOSIS IN THE MEDIA OF THE AORTIC WALL AND ITS RELATIONSHIP WITH AORTIC VALVE MORPHOLOGY IN AORTIC DILATATION

H. Edwards, J. Dargan, L. Elliot, A. Modi, S. Ohri, P. Townsend
Pages: 136 - 136
Background: The aortic valve is normally tricuspid but may vary in that it can be made up of 1, 2 or 4 leaflets with each of these often associated with aortopathy, most commonly aortic dilatation. In patients with a bicuspid valve this association has been explained in part by molecular changes taking...
Conference Abstract

P4.04 BARORECEPTOR SENSITIVITY IS REVERSED IN DIABETES AND IS UNAFFECTED BY ANTI-HYPERTENSIVE TREATMENT: A RODENT STUDY

Z. Kouchaki, E. Salum, J. Kals, P. Kampus, A.P. Avolio, M. Butlin
Pages: 136 - 136
Objectives: Diabetes is a complex disease associated with cardiovascular complications. This study compared baroreceptor sensitivity (BRS) in diabetic rats with and without anti-hypertensive treatment. Methods: Diabetes (induced by intraperitoneal injection of streptozotocin at 6 weeks of age) and control...
Conference Abstract

P3.2 IMPAIRED SYSTOLIC FUNCTION IS ASSOCIATED WITH ALTERED FORWARD WAVE INTENSITY

B. Hametner, T. Weber, S. Parragh, B. Eber, S. Wassertheurer
Pages: 136 - 136
Conference Abstract

P4.05 POLYCYSTIN DEFICIENCY RESULTS IN COMPLETE LOSS OF NO SYNTHESIS DURING SUSTAINED FLOW-MEDIATED DILATATION OF CONDUIT ARTERIES IN AUTOSOMAL DOMINANT POLYCYSTIC KIDNEY DISEASE: POSSIBLE REVERSAL BY DOPAMINE

A. Lorthioir, R. Joannidès, I. Rémy-Jouet, C. Fréguin-Bouilland, M. Iacob, C. Monteil, D. Lucas, M.P. Audrezet, D. Guerrot, V. Richard, C. Thuillez, M. Godin, J. Bellien
Pages: 136 - 137
Objectives: Autosomal dominant polycystic kidney disease (ADPKD) is due to mutations in genes PKD1 and PKD2 encoding polycystin-1 and -2, which transduce flow variations into cellular signals in the renal epithelium but also in vascular endothelium. However, the impact of polycystin deficiency on the...
Conference Abstract

P3.3 CARDIAC 82RB-PET/CT REVEALS MICROVASCULAR DYSFUNCTION IN ASYMPTOMATIC PATIENTS WITH TYPE 2 DIABETES

T. Hansen, B. Scholten, P. Hasbak, T. Christensen, A. Ghotbi, A. Kjaer, P. Rossing
Pages: 137 - 137
Conference Abstract

P4.06 ARTERIAL STIFFNESS CORRELATES WITH VITAMIN D DEFICIENCY IN HYPERTENSIVE PATIENTS WITH STAGE 3 CHRONIC KIDNEY DISEASE INDEPENDENTLY OF BLOOD PRESSURE

Rodilla Sala Enrique, Costa Muñoz José Antonio, Taverner Marta, Pascual Izuel José María, Malek Marín Tamara
Pages: 137 - 137
Objectives: To assess the prevalence of vitamin D deficiency and hyperparathyroidism as well as their relationship to blood pressure and arterial stiffness in hypertensive patients with stage 3 chronic kidney disease (CKD). Methods: Cross-sectional study that included 134 treated hypertensives (76 women,...
Conference Abstract

P3.4 FUNCTIONAL CHANGES IN THE CAROTID ARTERY ASSOCIATED WITH AN ACUTE BOUT OF RESISTANCE EXERCISE

J. Black, K. Stone, M. Stembridge, D. Newcombe, E. Assasie, E. Stӧhr, J. Esformes
Pages: 137 - 137
Conference Abstract

P4.07 EFFECTS OF ANTI-HYPERTENSIVE TREATMENT ON FUNCTIONAL AND STRUCTURAL COMPONENTS OF LARGE ARTERY STIFFNESS IN A RODENT MODEL OF TYPE I DIABETES

E. Salum, A.P. Avolio, J. Kals, P. Kampus, M. Butlin
Pages: 137 - 137
Objectives: Diabetes is associated with cardiovascular risk and increased arterial stiffness. Whether large artery stiffness is associated with diabetes per se or concomitant hypertension is currently unknown. Methods: Male, Wistar rats (6 weeks) were divided into control (n=8), control with anti-hypertensive...
Conference Abstract

P4.08 INSULIN RESISTANCE IS THE MAIN TARGET IN PREVENTING ACCELERATING ARTERIAL AGING

I.S. Strazhesko, O.N. Tkacheva, D.U. Akasheva, A.S. Kruglikova, E.V. Plokhova, O.U. Isaykina, M.S. Poktovskaya, V.A. Vygodin, V.S. Pykhtina, S.A. Boytsov
Pages: 137 - 138
Objectives: Increased arterial stiffness (AS) is the most prominent feature of arterial aging. It has been shown an association of AS not only with age, but also with insulin resistance (IR). Leukocyte telomere length (TL) has been proposed as an independent predictor of CVD. The origin of the association...
Short Communication

Hemodynamic impacts of entrainment of heart rate and stride rate

Mandeep S. Dhindsa, Jun Sugawara, Hirofumi Tanaka
Pages: 136 - 140
Synchronization of heart rate and step rate has been hypothesized to create a hemodynamically favorable situation where heart motion and bodily motion are in constant harmony so that stroke volume and cardiac output enhanced and oxygen delivery to the tissues is increased. The primary aim of the present...
Conference Abstract

1.1 PROGNOSTIC VALUE OF COMBINED ASSESSMENT OF AORTIC STIFFNESS AND CALCIFICATION IN DIALYSIS PATIENTS: OUTCOME DATA OF THE CALCIFICATION OUTCOME IN RENAL DISEASE (CORD) STUDY

F. Verbeke, W. Van Biesen, E. Honkanen, B. Wikström, P.B. Jensen, J.M. Krzesinski, M. Rasmussen, R. Vanholder, P.L. Rensma
Pages: 138 - 138
Conference Abstract

P4.09 DIFFERENT EFFECTS OF 7-NITROINDAZOLE AND L-NAME ADMINISTERED INDIVIDUALLY AND/OR TOGETHER ON CARDIOVASCULAR SYSTEM OF ADULT WISTAR RATS

Kristek Frantisek, Malekova Magdalena, Cacanyiova Sona
Pages: 138 - 138
Objectives: We evaluate the effect of NG-nitro-L-arginine methylester (L-NAME) and 7-nitroindazole (7NI) administered individually and/or together on cardiovascular system of adult Wistar rats. Methods: L-NAME (50 mg/kg/day in tap water) and 7NI (10 mg/kg/day in pellets) was administered to Wistar rats...
Conference Abstract

P4.11 SERUM UREA IS A NEW BIOMARKER OF CELLULAR AND VASCULAR AGING

V. Pykhtina, I. Strazhesko, D. Akasheva, A. Kruglikova, E. Plokhova, O. Isaykina, O. Tkacheva, S. Boytsov
Pages: 138 - 138
Objective: Large arteries stiffness is a feature of arterial aging and a predictor of cardiovascular diseases. The length of telomere (TL) in leukocytes is widely considered as a biomarker for cellular aging, cardiovascular aging and cardiovascular diseases. High concentrations of urea is known to increase...
Conference Abstract

1.3 PROGNOSTIC VALUE OF CAROTID-FEMORAL PULSE WAVE VELOCITY FOR CARDIOVASCULAR EVENTS: AN IPD META-ANALYSIS OF PROSPECTIVE OBSERVATIONAL DATA FROM 14 STUDIES INCLUDING 16,358 SUBJECTS

Y. Ben-Shlomo, M. Spears, C. Boustred, M. May, S. Anderson, P. Boutouyrie, J. Cameron, C.H. Chen, J.R. Cockcroft, K. Cruickshank, S.J. Hwang, E. Lakatta, S. Laurent, J. Maldonado, C.M. McEniery, G. Mitchell, S. Najjar, A. Newman, M. Ohishi, B. Pannier, T. Pereira, T. Shokawa, K. Sutton-Tyrell, D. Webb, T. Willum-Hansen, S. Zoungas, I.B. Wilkinson
Pages: 138 - 139
Conference Abstract

P3.9 METABOLOMIC SIGNATURE OF ARTERIAL STIFFNESS IN PATIENTS WITH PERIPHERAL ARTERIAL DISEASE

M. Zagura, J. Kals, K. Paapstel, K. Kilk, M. Serg, P. Kampus, J. Eha, U. Soomets, M. Zilmer
Pages: 138 - 138
Conference Abstract

P4.12 A COMPARISON OF DIFFERENT METHODS TO DETERMINE AORTIC PULSE WAVE VELOCITY IN ANEURYSMATIC AND CONTROL MICE

B. Trachet, R. Fraga-Silva, F.J. Londono-Hoyos, P. Segers, N. Stergiopulos
Pages: 138 - 139
Introduction: Accurate determination of aortic pulse wave velocity (PWV) in mice is not straightforward, due to the high resolution needed in both time and space. We compared different techniques in control and aneurysmatic mice. Methods: N=30 male, 18 weeks-old C57Bl/6 mice were included. N=20 animals...
Review Article

Monoclonal Antibodies in Oncology and their Effect on Arterial Stiffness – A Systematic Review

Eirini Solomou, Konstantinos Aznaouridis, Dimitrios Terentes-Printzios, Maria Drakopoulou, Konstantinos Toutouzas, Dimitris Tousoulis, Charalambos Vlachopoulos
Pages: 137 - 142
Introduction: Malignancies are the second leading cause of death worldwide. Treatment Monoclonal Antibody (MAbs)-based treatment of cancer has been established as one of the most successful therapeutic strategies in the last 20 years; however, there is a growing concern about the effects of these agents...