Artery Research

Volume 7, Issue 1, March 2013
Conference Abstract

1. P4.02 Assessing ventricular–vascular interactions non-invasively in healthy adolescents☆

T.J. Bradley, C. Slorach, C. Manlhiot, W. Hui, M.K. Friedberg, E.T. Jaeggi, P.F. Kantor, L. Mertens
Pages: 1 - 1
Background: Characterization of normal ventricular–vascular interactions by non-invasive assessment in healthy adolescents may provide new mechanistic insights into altered physiological states in congenital and acquired heart disease in this age group. Methods: Ventricular and vascular measures were...
Mini Review

2. Ventricular–arterial coupling: Invasive and non-invasive assessment

Julio A. Chirinos
Pages: 2 - 14
Interactions between the left ventricle (LV) and the arterial system, (ventricular–arterial coupling) are key determinants of cardiovascular function. Ventricular–arterial coupling is most frequently assessed in the pressure–volume plane using the ratio of effective arterial elastance (EA) to LV end-systolic...
Mini Review

3. Structural proteins and arterial ageing

Michael J. Sherratt
Pages: 15 - 21
In common with most dynamic tissues, the mechanical properties of arteries are determined by the relative composition and architecture of key structural extracellular matrix (ECM) proteins including fibrillar collagens and elastic fibre components. Although it is apparent that age-related loss of ECM...
Mini Review

4. Arterial stiffening: Causes and consequences

Marina Cecelja, Phil Chowienczyk
Pages: 22 - 27
Increased arterial stiffness, as measured by pulse wave velocity, is increasingly recognised as an important predictor of future cardiovascular events. At present, the mechanisms leading to stiffening of large arteries and the processes underlying the association between arterial stiffness and cardiovascular...
Review Article

5. MicroRNAs associated with the pathways involved in the pathogenesis of abdominal aortic aneurysms

P.W. Stather, J.B. Wild, N. Sylvius, E. Choke, R.D. Sayers, M.J. Bown
Pages: 28 - 35
Objectives: MicroRNAs (miRNAs) are small non-coding RNAs that regulate gene expression at a post-transcriptional level. Through binding to mRNA sequences, miRNAs have a wide variety of functions, and are key regulators in vascular disease. Although there are only 2 papers looking directly at the association...
Research Article

6. Vascular compliance during insulin infusion and oral glucose challenge

Houry Puzantian, Ari Mosenkis, Raymond R. Townsend
Pages: 36 - 41
Background: Vascular stiffness predicts cardiovascular disease (CVD). Pulse wave velocity (PWV), reflecting vascular stiffness, though determined largely by mean arterial pressure; is also sensitive to insulin and glucose. Capacitance in small (C2) and large vessels (C1), reflecting vascular responsiveness...
Research Article

7. Gender difference in age-related carotid stiffness: A prospective study in Chinese diabetic patients

Bo Zhao, Yan-Ping Liu, Yifei Zhang, Yuhong Chen, Zhifang Yang, Ying Zhu, Weiwei Zhan
Pages: 42 - 47
Background: The reason for the particularly increased cardiovascular morbidity and mortality in diabetic women remains unclear. The purpose of our study was to prospectively investigate sex difference in carotid stiffness in elder Chinese patients with type-2 diabetes mellitus (T2DM). Methods: 109 T2DM...
Research Article

8. The cardio-ankle vascular index predicts chronic kidney disease in Japanese subjects

Daisuke Maebuchi, Munehisa Sakamoto, Jun Fuse, Hiroaki Tanaka, Yasuyuki Shiraishi, Makoto Takei, Yumiko Inui, Yuumi Sutoh, Yukinori Ikegami, Yukihiko Momiyama
Pages: 48 - 53
Objective: Chronic kidney disease (CKD) is known to be associated with the incidence and mortality of cardiovascular disease. Therefore, the prevention of CKD may improve the mortality of cardiovascular disease. The risk factors of CKD are variable and multifactorial, similar to atherosclerosis. We hypothesized...
Research Article

9. Association between endothelial NO synthase polymorphism (rs3918226) and arterial properties

Jitka Seidlerová, Jan Filipovský, Otto Mayer, Renata Cífková, Martin Pešta, Radek Blatný, Jiří Vaněk
Pages: 54 - 59
Background: Recently, rs3918226 polymorphism in the promoter region of endothelial NO synthase (eNOS) was strongly associated with arterial hypertension in a large genome-wide association study. We investigated whether this polymorphism was associated with arterial phenotypes in a Czech general population. Methods:...
Research Article

10. Gender as a moderator in the relationship between anxiety and carotid intima-media thickness: The PREVENCION study

Diana A. Chirinos, Belissa Salinas-Najarro, Roberto Paz-Manrique, Zubair Khan, Waheed Raja, Francisco Ibañez, Fernando Corrales-Medina, Humberto Zea-Diaz, Julio A. Chirinos, Josefina Medina-Lezama
Pages: 60 - 66
Background: Previous studies regarding the association of atherosclerotic risk and anxiety have yielded conflicting results. Carotid intima–media thickness (cIMT) is an early marker of subclinical atherosclerosis and an independent predictor of cardiovascular risk. We aimed to determine the relationship...
Research Article

11. Effects of curcumin intake and aerobic exercise training on arterial compliance in postmenopausal women

Nobuhiko Akazawa, Youngju Choi, Asako Miyaki, Yoko Tanabe, Jun Sugawara, Ryuichi Ajisaka, Seiji Maeda
Pages: 67 - 72
Background: Reduction in arterial compliance with aging increases the risk of cardiovascular disease. Lifestyle modification, particularly aerobic exercise and dietary modification, has a favorable effect on vascular aging. Curcumin, a major component of turmeric, is an anti-inflammatory agent. Therefore,...