Effects of curcumin intake and aerobic exercise training on arterial compliance in postmenopausal women

Nobuhiko Akazawa; Youngju Choi; Asako Miyaki; Yoko Tanabe; Jun Sugawara; Ryuichi Ajisaka; Seiji Maeda

doi:10.1016/j.artres.2012.09.003

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Volume 7, Issue 1, March 2013, Pages 67 - 72

Effects of curcumin intake and aerobic exercise training on arterial compliance in postmenopausal women

Authors

Nobuhiko Akazawa^a, Youngju Choi^b, Asako Miyaki^a, Yoko Tanabe^a, Jun Sugawara^c, Ryuichi Ajisaka^b, Seiji Maeda^b^{, *}

^aGraduate School of Comprehensive Human Science, University of Tsukuba, 1-1-1 Tennodai, Tsukuba, Ibaraki 305-8577, Japan

^bFaculty of Health and Sport Sciences, University of Tsukuba, 1-1-1 Tennodai, Tsukuba, Ibaraki 305-8577, Japan

^cHuman Technology Research Institute, National Institute of Advanced Industrial Science and Technology (AIST), 1-1-1 Higashi, Tsukuba, Ibaraki 305-8566, Japan

^*Corresponding author. Tel.: +81 29 853 2683; fax: +81 29 853 2986. E-mail address: maeda@taiiku.tsukuba.ac.jp (S. Maeda).

Corresponding Author

Seiji Maeda

Received 9 July 2012, Revised 20 August 2012, Accepted 3 September 2012, Available Online 26 September 2012.

DOI: 10.1016/j.artres.2012.09.003 How to use a DOI?
Keywords: Arterial stiffness; Lifestyle modification; Physical activity; Turmeric
Abstract: Background: Reduction in arterial compliance with aging increases the risk of cardiovascular disease. Lifestyle modification, particularly aerobic exercise and dietary modification, has a favorable effect on vascular aging. Curcumin, a major component of turmeric, is an anti-inflammatory agent. Therefore, it is plausible to hypothesize that curcumin improves arterial compliance. We investigated the effects of curcumin ingestion alone and in combination with aerobic exercise training on arterial compliance in postmenopausal women.

Methods: A total of 51 postmenopausal women were assigned to 4 groups: placebo, curcumin, exercise and placebo (Ex + placebo), and exercise and curcumin (Ex + curcumin). Curcumin or placebo was ingested orally for 8 weeks. The exercise groups underwent moderate aerobic exercise training for 8 weeks.

Results: Carotid arterial compliance increased significantly in the curcumin, Ex + placebo, and Ex + curcumin groups, whereas no such changes were observed in the placebo control group. The magnitude of increases in carotid arterial compliance was the greatest in the Ex + curcumin group.

Conclusion: We concluded that curcumin ingestion improves carotid arterial compliance and that the combination of curcumin and aerobic exercise training was more efficacious in increasing central arterial compliance than either of these treatments alone in postmenopausal women.
Open Access: This is an open access article distributed under the CC BY-NC license.

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<Previous Article In Issue

Journal: Artery Research
Volume-Issue: 7 - 1
Pages: 67 - 72
Publication Date: 2012/09/26
ISSN (Online): 1876-4401
ISSN (Print): 1872-9312
DOI: 10.1016/j.artres.2012.09.003 How to use a DOI?
Open Access: This is an open access article distributed under the CC BY-NC license.

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ris enw bib

TY  - JOUR
AU  - Nobuhiko Akazawa
AU  - Youngju Choi
AU  - Asako Miyaki
AU  - Yoko Tanabe
AU  - Jun Sugawara
AU  - Ryuichi Ajisaka
AU  - Seiji Maeda
PY  - 2012
DA  - 2012/09/26
TI  - Effects of curcumin intake and aerobic exercise training on arterial compliance in postmenopausal women
JO  - Artery Research
SP  - 67
EP  - 72
VL  - 7
IS  - 1
SN  - 1876-4401
UR  - https://doi.org/10.1016/j.artres.2012.09.003
DO  - 10.1016/j.artres.2012.09.003
ID  - Akazawa2012
ER  -

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