Proceedings of the 1st International Integrative Conference on Health, Life and Social Sciences (ICHLaS 2017)

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Screening of ß-Globin Gene Mutations in Adolescent Schoolgirls in Rural Malang and Sukabumi City, Java Province, Indonesia

Authors
Chris Adhiyanto, Yanti Susianti, Nurlaely M Rahmawati, Fase Badriah, Zeti Harriati, Raisha Raisha, Ajeng RS Putri, Asry Nurvitasari, Umi Fahmida, Annasari Mustafa
Corresponding Author
Chris Adhiyanto
Available Online December 2017.
DOI
10.2991/ichlas-17.2017.47How to use a DOI?
Keywords
thalassemia; anemia in adolescents; Malang; Sukabumi; Indonesia; CD26, and IVS1nt
Abstract

Anemia is one of the major health problems in Indonesia. In general, the condition occurs because of iron deficiency. Another major factor that causes anemia in Indonesia is thalassemia. Usually, the thalassemia patient comes with severe anemia for treatment. Since thalassemia is a genetic disorder, it is necessary to know how to prevent and reduce the incidence. The purpose of this study was to determine the prevalence of thalassemia trait, ß-globin gene mutants among adolescent schoolgirls in rural Malang area and Sukabumi City. The early detection of thalassemia will encourage early counseling and treatment. The result of this study found that among 180 adolescent schoolgirls from Malang and Sukabumi, 22 were carrying thalassemic ß-globin genes with asymptomatic to mild anemic conditions. Only one of the students had symptoms of intermediate thalassemia. The polymorphism encountered was CD26 in Malang and IVS1nt5 in Sukabumi City.

Copyright
© 2017, the Authors. Published by Atlantis Press.
Open Access
This is an open access article distributed under the CC BY-NC license (http://creativecommons.org/licenses/by-nc/4.0/).

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Volume Title
Proceedings of the 1st International Integrative Conference on Health, Life and Social Sciences (ICHLaS 2017)
Series
Advances in Health Sciences Research
Publication Date
December 2017
ISBN
10.2991/ichlas-17.2017.47
ISSN
2468-5739
DOI
10.2991/ichlas-17.2017.47How to use a DOI?
Copyright
© 2017, the Authors. Published by Atlantis Press.
Open Access
This is an open access article distributed under the CC BY-NC license (http://creativecommons.org/licenses/by-nc/4.0/).

Cite this article

risenwbib
TY  - CONF
AU  - Chris Adhiyanto
AU  - Yanti Susianti
AU  - Nurlaely M Rahmawati
AU  - Fase Badriah
AU  - Zeti Harriati
AU  - Raisha Raisha
AU  - Ajeng RS Putri
AU  - Asry Nurvitasari
AU  - Umi Fahmida
AU  - Annasari Mustafa
PY  - 2017/12
DA  - 2017/12
TI  - Screening of ß-Globin Gene Mutations in Adolescent Schoolgirls in Rural Malang and Sukabumi City, Java Province, Indonesia
BT  - Proceedings of the 1st International Integrative Conference on Health, Life and Social Sciences (ICHLaS 2017)
PB  - Atlantis Press
SP  - 9
EP  - 12
SN  - 2468-5739
UR  - https://doi.org/10.2991/ichlas-17.2017.47
DO  - 10.2991/ichlas-17.2017.47
ID  - Adhiyanto2017/12
ER  -