Mitotic Index In Invasive Ductal Carcinoma Nst (IDC-Nst) of Breast and Its Relation With Tumor Size and Regional Lymph Nodes Status

DOI

10.2991/ichlas-17.2017.3How to use a DOI?

Keywords

mitotic index; tumor size; regional lymph node involvement; invasive ductal carcinoma NST of breast

Abstract

Until nowadays, breast cancer is still the highest malignancy in women in both the developing and developed countries. The main causes of death in breast cancer is metastasis. Patients who have experienced distant metastases have a poor prognosis. Proliferation is a biological process that is important for its role in growth and in maintaining tissue homeostasis, so that cell proliferation assessment is often used to predict the behavior of tumors, among others, the potential for recurrence, metastasis potential, to the ability to survive. Plays an important role in the proliferation of invasive breast cancer. Increased proliferation strongly linked with a poor prognosis. This is because an increase in proliferation significant increase in the aggressiveness of the tumor. Mitotic index is one of proliferation assessment that used in breast cancer histopathological staging. Objective: to know the relationship between mitotic index, tumor size, regional lymph node involvement, in invasive ductal breast carcinoma NST. The 47 paraffin block preparations of invasive ductal breast carcinoma NST obtained from the Jakarta Breast Center the period 2008-2011 conducted hematoxylin eosin staining (HE) to calculate mitotic index. Secondary data such as age, histopathological diagnosis and grading, tumor diameter, and the involvement of lymph nodes obtained from medical record of histopathological examination result sheets. Analysis with Chi-square test and Spearman. There is no correlation between mitotic index, tumor size, regional lymph node involvement on invasive ductal carcinoma (IDC-NST) of breast in this study.

Copyright

© 2017, the Authors. Published by Atlantis Press.

Open Access

This is an open access article distributed under the CC BY-NC license (http://creativecommons.org/licenses/by-nc/4.0/).

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TY  - CONF
AU  - Dyah Ayu Woro Setyaningrum
AU  - N.C. Siregar
AU  - H. Tjahjadi
PY  - 2017/12
DA  - 2017/12
TI  - Mitotic Index In Invasive Ductal Carcinoma Nst (IDC-Nst) of Breast and Its Relation With Tumor Size and Regional Lymph Nodes Status
BT  - Proceedings of the 1st International Integrative Conference on Health, Life and Social Sciences (ICHLaS 2017)
PB  - Atlantis Press
SN  - 2468-5739
UR  - https://doi.org/10.2991/ichlas-17.2017.3
DO  - 10.2991/ichlas-17.2017.3
ID  - Setyaningrum2017/12
ER  -