Intensive Care Research

Volume 1, Issue 1-2, June 2021
Review Article

2. Mesenchymal Stem Cells in Sepsis: From Basic Research to Clinical Application

Junyi Sun, Xianfei Ding, Tongwen Sun
Pages: 2 - 10
Sepsis is a life-threatening organ dysfunction caused by a deregulated host response to infection, and is the most common cause of death in the intensive care unit. Although the pathogenesis of sepsis has made substantial progress, the current clinical treatment of sepsis is basically symptomatic treatment,...
Review Article

3. Overview of the Cardiotoxicity Induced by PD-1/PD-L1 Immune Checkpoint Inhibitor in Critical Care

Ruiting Li, Xiaojing Zou, Huaqing Shu, You Shang
Pages: 11 - 15
The Programmed Cell Death 1 (PD-1)/Programmed Death Ligand 1 (PD-L1) Immune Checkpoint Inhibitors (ICIs), have become a hot spot in the field of cancer research and treatment, and bring new hope to patients with advanced tumors. But, in addition to enhancing the anti-tumor effect of T cells, PD-1/PD-L1...
Research Article

4. The Incidence and Prognosis of ICU Delirium: A Retrospective Study from a Single Center

Qing Feng, Yuhang Ai, Meilin Ai, Li Huang, Qianyi Peng, Lina Zhang
Pages: 16 - 23
Purpose: Delirium is a frequent occurrence amongst Intensive Care Unit (ICU) patients, but studies on its causes are sparse and its risk factors vary from disease to disease. Here, in this study, an attempt was made to investigate the factors associated with the prognosis of delirium in the ICU. Methods:...
Research Article

5. Preliminary Efficacy of Tocilizumab Treatment in the Patients with COVID-19

Yu Chen, Xijing Zhang
Pages: 24 - 30
Background: Interleukin-6 (IL-6) was considered to be with the severity and mortality in COVID-19 patients, which implies a potential therapeutic target for treatment. We aimed to evaluate the safety and initial efficacy of Tocilizumab treatment for COVID-19 patients. Methods: In the retrospective study,...
Case Report

6. Unusually High Global End Diastolic Index Associated with Optimal Cardiac Index in Two Critically Ill Patients

Xiaoqing Wu, Desheng Chen, Chen Li, Jun Duan
Pages: 31 - 33
The optimal management of hemodynamic disorders among critically ill patients requires an accurate assessment of hemodynamic status. Global End Diastolic Index (GEDI) is taken for a more reliable indicator of preload in critically ill patients than central venous pressure and doctors tend to arrange...