This study was aimed to determine the risk factors associated with COVID-19 infection among contacts of index cases in Saudi Arabia. This unmatched case–control study was conducted among contacts of confirmed COVID-19 cases in April and May 2020 in Al-Madinah, Saudi Arabia. A total of 118 cases and 115...

Congenital cutaneous candidiasis is a rare disease that is usually misdiagnosed as a type of benign neonatal eruption. We report on a preterm infant born with diffuse skin rashes that evolved into various forms and misleading the diagnosis. The persistence of respiratory distress and worsening of chest...

Infection by the emerging, potentially zoonotic Middle East Respiratory Syndrome Coronavirus (MERS-CoV) presents a severe health hazard to humans and is often fatal. Given the lack of particular medicines against MERS-CoV, drug discovery studies are needed to bridge this knowledge gap. In this study,...

Large vessel involvement and arterial aneurysms are not typically encountered in Granulomatosis with Polyangiitis (GPA), which is a small vessel disease. We report the case of a 70-year-old male presenting with a ruptured hepatic artery aneurysm and elevated Antineutrophil Cytoplasmic Autoantibody, Cytoplasmic...

The SARS-CoV-2-induced novel coronavirus disease has become a global pandemic. As the latest coronavirus variants are even more infectious and deadly, its treatment is very difficult. Currently used drugs such as remdesivir, saquinavir, and chloroquine have several drawbacks. Recent studies have reported...

Under-five mortality is a substantial indicator of children’s health, well-being, and consequently, socioeconomic development of a country. The primary focus of this study was to estimate the prevalence and identify the factors associated with under-5 mortality in Nigeria. This research utilized the...

Background: A systematic review with meta-analysis was conducted to assess the association of glucocorticoids use with the likelihood of all-cause mortality in cases with Coronavirus Disease 2019 (COVID-19). Methods: Databases and cross-referencing were searched for observational studies about patients...

This study sought to examine the relationship between knowledge, attitude, and acceptance of Coronavirus Disease 2019 (COVID-19) vaccine among students in selected universities in Nigeria. An anonymous survey was conducted online among Nigeria students. The questionnaire collected demographic characteristics,...

The Coronavirus Disease 2019 (COVID-19) pandemic has critically struck healthcare systems and burdened emergency services. To date, there is no accurate and rapid point-of-care diagnostic test. This study aimed to investigate Lung Ultrasound (LUS) against Reverse Transcription-Polymerase Chain Reaction...

Thoracic Endovascular Aortic Repair (TEVAR) became the standard treatment for patients with Blunt Thoracic Aortic Injury (BTAI) because it is a minimally invasive intervention, with proven lower morbidity and mortality compared with open surgery, especially in multiple trauma patients. However, there...

A drug repurposing approach for Food and Drug Administration (FDA)-approved drugs and preclinical entity by using cheminformatics and chemical transformational method, with the objective of discovering safer novel potent inhibitors that are selective for COVID-19, is reported. We examined the action...

Hospital-acquired Respiratory-Tract Infections (HARTIs) are identified as the most frequent type of hospital-acquired infections. They can engender significant morbidity and mortality rates, generating a heavy economic burden, especially in the limited resources countries. In this perspective, this study...

Neonatal Hemochromatosis (NH) is a rare phenotype of severe fetal/neonatal liver injury that is accompanied by extrahepatic siderosis. Current clinical evidence shows that NH is not a disease per se, but is the consequence of fetal liver injury. Gestational alloimmune liver disease is the cause of nearly...

Coronavirus disease 2019 (COVID-19) continues to spread worldwide since its emergence in December 2019 in Wuhan, China, and as of January 3, 2021 more than 84.4 million cases and 1.8 million deaths have been reported. To predict COVID-19 cases in Algeria, we applied two models—the logistic growth model...

Although several guidelines for Stress Ulcer Prophylaxis (SUP) have been published, Acid-Suppressive Therapy (AST) remains largely prescribed in hospitalized patients. Thus, our study aimed to evaluate the current practice surrounding SUP in Soba University Hospital (Khartoum, Sudan). This descriptive...

The prediction of bony involvement of the mandible in oral Squamous Cell Carcinoma (SCC) by taking imaging scans prior to surgery is an important issue. The objective of our study was to determine the diagnostic accuracy of Multiple Detector Computed Tomography (MDCT) in detecting mandibular involvement...

Developing countries such as Belize have been facing profound challenges in their quest to effectively track cases of Coronavirus Disease 2019 (COVID-19) and contain the pandemic within their own territory. We assume that at the heights of a COVID-19 wave the number of daily reported cases are substantially...

Coronavirus Disease 2019 (COVID-19) is a major challenge for health systems worldwide. Molecular diagnosis is a cornerstone in the management of COVID-19. Clinicians should understand the various aspects of molecular testing that may influence their judgment and management. Cycle threshold, viral shedding,...

Thanks to the high vaccination rates posted in Israel and the United Arab Emirates since mid-December 2020, by end of March 2021 a significant portion of the population has been vaccinated. This adds to the percentage of those who have been infected and have recovered, protected to a different extent...

Cytokine storm is the major cause of death in patients with acute respiratory distress caused by COVID-19. Because cytokine storm is a life-threatening condition, it is important to treat patients with the most appropriate drugs depending on their infectious pathogen and medical status. In this short...

Background: Human Immunodeficiency Virus (HIV) positive patients are likely to be at risk of other infectious pathogens such as Hepatitis B Virus (HBV). HIV and HBV are blood-borne pathogens and are transmitted via intravenous drug use, sexual contact, or mother to child during pregnancy or birth. Objective:...

Multiple Sclerosis (MS) is an autoimmune disorder affecting the central nervous system, characterized by demyelination of the neurons with limited remyelination. There has been a rising trend toward associating a history of allergy with MS. Both MS and type 1 allergies are developed by a hyper-reactive...

The presentation of congenital intestinal stenosis in neonates can vary from mild intermittent feeding intolerance resulting in difficulty of clinical judgment to profound obstruction. This report describes one case of ileal stenosis whose radiological investigations were not favoring intestinal obstruction...

Proponents of the Sub-Vastus (SV) approach in primary Total Knee Arthroplasty (TKA) claim superior extensor mechanism function which results in earlier recovery after surgery. We performed a meta-analysis of randomized controlled trials comparing the SV and standard Medial Parapatellar (MPP) approaches...