Adherence to Stress Ulcer Prophylaxis Guideline in Medicine Unit at Soba University Hospital: A Descriptive Retrospective Study

Authors

Alaa A. Elmubarak¹, Safaa Badi^2, , Bashir A. Yousef^{3, *,}

¹Department of Clinical Pharmacy, Faculty of Pharmacy, University of Khartoum, Al-Qasr Ave, Khartoum 11111, Sudan

²Department of Clinical Pharmacy, Faculty of Pharmacy, Omdurman Islamic University, Aboseid Street, Khartoum 11111, Sudan

³Department of Pharmacology, Faculty of Pharmacy, University of Khartoum, Al-Qasr Ave, Khartoum 11111, Sudan

^*Corresponding author. Email: bashiralsiddiq@gmail.com

DOI

10.2991/dsahmj.k.210624.001How to use a DOI?

Keywords

Acid-suppressive therapy; guidelines; Soba University Hospital; stress ulcer prophylaxis

Abstract

Although several guidelines for Stress Ulcer Prophylaxis (SUP) have been published, Acid-Suppressive Therapy (AST) remains largely prescribed in hospitalized patients. Thus, our study aimed to evaluate the current practice surrounding SUP in Soba University Hospital (Khartoum, Sudan). This descriptive cross-sectional hospital-based retrospective study was conducted in the medicine unit of Soba University Hospital. The sample size was 317 participants, and data were collected from medical records from January to December 2018 using a validated checklist. SPSS was applied for data analysis. The mean age of patients was 53 ± 16.8 years, and 170 (54%) of them were female. The mean duration of hospital stay was 10 ± 7.4 days. Seventy-four percent of patients who received prophylaxis did not have an indication for SUP. The majority (116; 36.5%) of patients who were administered parenteral drugs can tolerate oral medications. Overall, the dose of acid-suppressant drugs was optimal in all patients. Proton Pump Inhibitors (PPIs), especially pantoprazole, are the dominant AST used (314; 99.1%). Moreover, 315 (99.4%) of the study population were taking medication during hospitalization and two (1%) patients were discharged with AST. The study concluded that SUP was administered to noncritically ill hospitalized patients who lacked or had few risk factors for gastrointestinal bleeding. PPIs were the overwhelming choice among practitioners. Collectively, the study showed low adherence to guidelines when prescribing (AST) outside critical care settings. Therefore, there is an urgent need for implementation of practical guidelines in noncritical care settings.

Copyright

© 2021 Dr. Sulaiman Al Habib Medical Group. Publishing services by Atlantis Press International B.V.

Open Access

This is an open access article distributed under the CC BY-NC 4.0 license (http://creativecommons.org/licenses/by-nc/4.0/).

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TY  - JOUR
AU  - Alaa A. Elmubarak
AU  - Safaa Badi
AU  - Bashir A. Yousef
PY  - 2021
DA  - 2021/06/29
TI  - Adherence to Stress Ulcer Prophylaxis Guideline in Medicine Unit at Soba University Hospital: A Descriptive Retrospective Study
JO  - Dr. Sulaiman Al Habib Medical Journal
SP  - 125
EP  - 130
VL  - 3
IS  - 3
SN  - 2590-3349
UR  - https://doi.org/10.2991/dsahmj.k.210624.001
DO  - 10.2991/dsahmj.k.210624.001
ID  - Elmubarak2021
ER  -