Artery Research

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Volume 20, Issue C, December 2017, Pages 84 - 84

P170 SHORT-TERM EFFECTS OF TRANSCATHETER AORTIC VALVE IMPLANTATION ON AORTIC FUNCTION AND HEMODYNAMICS

Authors
Dimitrios Terentes-Printzios, Charalambos Vlachopoulos, Konstantinos Toutouzas, Georgios Latsios, Andreas Synetos, Georgios Trantalis, Fani Mitropoulou, Maria Drakopoulou, Konstantinos Stathogiannis, Vicky Penesopoulou, Konstantinos Kalogeras, Konstantinos Aznaouridis, Manolis Vavuranakis, Dimitrios Tousoulis
Peripheral Vessels Unit, First Department of Cardiology, Hippokration Hospital, Medical School, National and Kapodistrian University of Athens, Athens, Greece
Available Online 6 December 2017.
DOI
10.1016/j.artres.2017.10.118How to use a DOI?
Abstract

Purpose/Background/Objectives: Aortic stiffness and hemodynamics are independent predictors of adverse cardiovascular events. Transcatheter aortic valve implantation (TAVI) is growingly used in elderly patients with aortic stenosis. We sought to investigate the effect of TAVI upon aortic vascular function and hemodynamics as well as the interplay between genders.

Methods: Twenty high-risk patients (mean age 82.2±5.3 years, 13 female) with severe symptomatic aortic stenosis undergoing TAVI were included. Aortic stiffness was estimated through carotid-femoral pulse wave velocity (PWV). Aortic hemodynamics (aortic pressures, aortic augmentation index [AIx]) and subendocardial viability ratio (SEVR) were measured with Sphygmocor. Measurements were conducted prior to the implantation and at discharge.

Results: PWV prior to the implantation was 8.6±1.5 m/s and aortic AIx = 33.0±14.0% for the overall population. There was no statistically significant change in peripheral or aortic pressures as well as on aortic stiffness after implantation of TAVI. However, there was a marginally non-significant trend for an increase in SEVR (116±28 vs 131±40%, p = 0.067). Results to the male population were similar to the overall population.

Conversely, in the female population, there was a significant increase in PWV after TAVI (8.4±1.2 m/s vs 8.9±1.3% with p = 0.034, respectively). Furthermore, there was a significant increase in SEVR after TAVI (107±28 vs 125±24% with p = 0.002, respectively). All other variables did not change significantly in the female population.

Conclusion: Our study shows that shortly after TAVI female subjects experience an increase in aortic stiffness with an improvement of myocardial perfusion. These findings further elucidate the short-term hemodynamic consequences of aortic valve repair.

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Journal
Artery Research
Volume-Issue
20 - C
Pages
84 - 84
Publication Date
2017/12/06
ISSN (Online)
1876-4401
ISSN (Print)
1872-9312
DOI
10.1016/j.artres.2017.10.118How to use a DOI?
Open Access
This is an open access article distributed under the CC BY-NC license.

Cite this article

risenwbib
TY  - JOUR
AU  - Dimitrios Terentes-Printzios
AU  - Charalambos Vlachopoulos
AU  - Konstantinos Toutouzas
AU  - Georgios Latsios
AU  - Andreas Synetos
AU  - Georgios Trantalis
AU  - Fani Mitropoulou
AU  - Maria Drakopoulou
AU  - Konstantinos Stathogiannis
AU  - Vicky Penesopoulou
AU  - Konstantinos Kalogeras
AU  - Konstantinos Aznaouridis
AU  - Manolis Vavuranakis
AU  - Dimitrios Tousoulis
PY  - 2017
DA  - 2017/12/06
TI  - P170 SHORT-TERM EFFECTS OF TRANSCATHETER AORTIC VALVE IMPLANTATION ON AORTIC FUNCTION AND HEMODYNAMICS
JO  - Artery Research
SP  - 84
EP  - 84
VL  - 20
IS  - C
SN  - 1876-4401
UR  - https://doi.org/10.1016/j.artres.2017.10.118
DO  - 10.1016/j.artres.2017.10.118
ID  - Terentes-Printzios2017
ER  -