Systemic and local effects of garlic administration in meat goats

DOI

10.2991/978-94-6463-282-8_20How to use a DOI?

Keywords

Animal Agriculture; Sustainable Animal Production; Garlic; Protein

Abstract

Animal agriculture is a major contributor to the United States economy. Livestock contributes about 13% of the energy to the world’s diet. Animal-source foods are good sources of high-quality protein and micronutrients that are essential for normal development and good health. Sustainable animal production requires that disease-causing pathogens be effectively controlled. Gastrointestinal parasites are a severe threat to goat production. The present study was carried out to determine the effect of garlic extracts on global gene transcription, protein secretion, and gut health indicators in meat goats. Garlic (Allium sativa) has been used as a medicinal herb since time immemorial in almost every known civilization. It has antibiotic, anti-helminthic, and anti-inflammatory properties. Twelve (N=12) adult female, clinically healthy Boer x Spanish goats were divided into 2 groups. The treatment group was drenched daily with a garlic barrier for 4 weeks. Fecal and blood samples were collected weekly. Total parasite Egg counts per gram of feces were evaluated using the Modified McMaster method. Total RNA was isolated using Trizol and evaluated for concentration and purity using the nanodrop spectrophotometer. Total plasma protein secretion was assessed using the BCA assay. All variables were analyzed using SAS 9.1 statistical analysis software (P≤0.05). The fecal egg count was reduced in animals treated with garlic over the 4-weeks. Garlic treatment significantly increased (P<0.0374) total plasma protein concentration. It also significantly reduced (P<0.037) the eggs per gram during the second and fourth weeks of treatment. The concentration of RNA varied during different weeks of treatment. There was a significant decrease in the transcription over time (P<0.01) but the purity remained almost similar. Garlic drenching can be an economic and eco-friendly approach to modulate global gene transcription, protein secretion, the gut microbiome in goats, or sustainable goat production. Temperature-controlled studies are needed. Target genes and protein pathways are under study.

Copyright

© 2023 The Author(s)

Open Access

Open Access This chapter is licensed under the terms of the Creative Commons Attribution-NonCommercial 4.0 International License (http://creativecommons.org/licenses/by-nc/4.0/), which permits any noncommercial use, sharing, adaptation, distribution and reproduction in any medium or format, as long as you give appropriate credit to the original author(s) and the source, provide a link to the Creative Commons license and indicate if changes were made.

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TY  - CONF
AU  - Sowmya Jagana
AU  - Sreenavya Inupala
AU  - Priyanka Pande
AU  - M. D. Rasel Uzzaman
AU  - Mulumebet Worku
PY  - 2023
DA  - 2023/11/22
TI  - Systemic and local effects of garlic administration in meat goats
BT  - Proceedings of the National Conference on Next-Generation Sustainable Technologies for Small-Scale Producers (NGST 2022)
PB  - Atlantis Press
SP  - 176
EP  - 185
SN  - 2468-5747
UR  - https://doi.org/10.2991/978-94-6463-282-8_20
DO  - 10.2991/978-94-6463-282-8_20
ID  - Jagana2023
ER  -