Morphological Characteristics of Drug-loaded Nanoparticles based on Microscope Images Analysis System
Bohua Feng, Siyuan Mo, Liufen Peng, Huoyan Xu
Available Online November 2012.
- https://doi.org/10.2991/citcs.2012.178How to use a DOI?
- component; Nanoparticle; Microscope Image Analysis; Morphological Characteristics
- Microscope images analysis of drug carriers was a widely used method for those nanomaterials. Usually manual measuring and analysis of microscope images were subject to errors, and bad stability of results. Nanoparticles microscope images analysis method was combined with computer image processing technique in this research. A new nanoparticle Rot/CMC-g-RA was prepared with chitosan derivate drug carrier CMC-g-RA and botanical drug rotenone (Rot), and a processing and measuring system for microscope images of those drug-loaded nanoparticles was prepared by Visual C++ 6.0. The result showed characteristics measured by the system such as nanoparticles, particle size, area and roundness of Rot/CMC-g- RA were close to that measured by dynamic light scattering (DLS) method. And a fast, precise and automatic method for measuring and statistic nanoparticles morphometric parameters was developed.
- Open Access
- This is an open access article distributed under the CC BY-NC license.
Cite this article
TY - CONF AU - Bohua Feng AU - Siyuan Mo AU - Liufen Peng AU - Huoyan Xu PY - 2012/11 DA - 2012/11 TI - Morphological Characteristics of Drug-loaded Nanoparticles based on Microscope Images Analysis System BT - 2012 National Conference on Information Technology and Computer Science PB - Atlantis Press SP - 698 EP - 701 SN - 1951-6851 UR - https://doi.org/10.2991/citcs.2012.178 DO - https://doi.org/10.2991/citcs.2012.178 ID - Feng2012/11 ER -