Proceedings of the 2nd International Conference on Social Science, Public Health and Education (SSPHE 2018)

Progress in Mechanism of E.coli K1 Crossing the Blood-brain Barrier

Authors
Xiao Yang, Huiwen Tian, Shaoyi Lin, Jie Li, Shenghe Huang, Hong Cao
Corresponding Author
Hong Cao
Available Online January 2019.
DOI
10.2991/ssphe-18.2019.48How to use a DOI?
Keywords
E. coli K1, blood-brain barrier, Meningitis
Abstract

Meningitis is a serious central nervous system disease, E. coli K1 is the main pathogen that causes it. E.coli K1 triggers meningitis only if it crosses the blood-brain barrier(BBB), but the detail mechanism of how E. coli K1 cross the blood-brain barrier is still unclear. This article is based on current research, according to the sequence of E. coli K1 crossing the blood-brain barrier, introduce the mechanism from three sections: severe bacteremia, adhesion and invasion to brain microvascular endothelial cells (BMEC), rearrangement of cytoskeleton.

Copyright
© 2019, the Authors. Published by Atlantis Press.
Open Access
This is an open access article distributed under the CC BY-NC license (http://creativecommons.org/licenses/by-nc/4.0/).

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Volume Title
Proceedings of the 2nd International Conference on Social Science, Public Health and Education (SSPHE 2018)
Series
Advances in Social Science, Education and Humanities Research
Publication Date
January 2019
ISBN
978-94-6252-653-2
ISSN
2352-5398
DOI
10.2991/ssphe-18.2019.48How to use a DOI?
Copyright
© 2019, the Authors. Published by Atlantis Press.
Open Access
This is an open access article distributed under the CC BY-NC license (http://creativecommons.org/licenses/by-nc/4.0/).

Cite this article

TY  - CONF
AU  - Xiao Yang
AU  - Huiwen Tian
AU  - Shaoyi Lin
AU  - Jie Li
AU  - Shenghe Huang
AU  - Hong Cao
PY  - 2019/01
DA  - 2019/01
TI  - Progress in Mechanism of E.coli K1 Crossing the Blood-brain Barrier
BT  - Proceedings of the 2nd International Conference on Social Science, Public Health and Education (SSPHE 2018)
PB  - Atlantis Press
SP  - 201
EP  - 205
SN  - 2352-5398
UR  - https://doi.org/10.2991/ssphe-18.2019.48
DO  - 10.2991/ssphe-18.2019.48
ID  - Yang2019/01
ER  -