Efficacy Of Temulawak Extract (Curcuma xanthorrhiza Roxb) in Reducing Ureum Levels of White Rats (Rattus Norvegicus) on Maximum Physical Activity: Pure Experimental Research

DOI

10.2991/978-94-6463-550-8_9How to use a DOI?

Keywords

Ginger Extract; Urea Levels; Maximum Physical Activity; Temulawak

Abstract

Maximum physical activity triggers a transformation of renal hemodynamics and increased protein catabolism, causing urea levels to rise. One natural source of antioxidants is ginger, which can reduce uranium levels. This aims to analyze the effect of ginger extract on urea levels during maximum physical activity. Using a pretest-posttest with control group (K) design, a total of 28 male rats were divided into four groups: control and three intervention groups provided with ginger extracts at various doses (P1: 6.75 mg/day; P2: 13.5 mg/day; P3: 20.25 mg/day) after performing maximum physical activity by swimming. Blood urea levels were measured afterwards and later analyzed using One Way Anova followed with LSD test. The results found increased urea (5.66 mg/dl) in group K, while all intervention groups showed lower levels, with group P3 having the highest difference (P1: 12.66 mg/dl; P2: 21.83 mg/dl; P3: 25.16 mg/dl). Statistical test revealed that low, medium, and high doses of ginger extract significantly affected urea levels in mice with maximum physical activity. Further post hoc test revealed significant difference between control and intervention groups. In conclusion, administering ginger extract at low, medium, and high doses can significantly reduce blood urea levels in mice with maximum physical activity.

Copyright

© 2024 The Author(s)

Open Access

Open Access This chapter is licensed under the terms of the Creative Commons Attribution-NonCommercial 4.0 International License (http://creativecommons.org/licenses/by-nc/4.0/), which permits any noncommercial use, sharing, adaptation, distribution and reproduction in any medium or format, as long as you give appropriate credit to the original author(s) and the source, provide a link to the Creative Commons license and indicate if changes were made.

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TY  - CONF
AU  - Ali Rosidi
AU  - Silvia Mayuri
AU  - Kartika Nugraheni
AU  - Zahra Maharani Latrobdiba
AU  - Ari Istiany
AU  - Hersanti Sulistyaningrum
AU  - Firdananda Fikri Jauharany
PY  - 2024
DA  - 2024/10/27
TI  - Efficacy Of Temulawak Extract (Curcuma xanthorrhiza Roxb) in Reducing Ureum Levels of White Rats (Rattus Norvegicus) on Maximum Physical Activity: Pure Experimental Research
BT  - Proceedings of the 2nd Lawang Sewu International Symposium on Health Sciences: Nutrition (LSISHSN 2023)
PB  - Atlantis Press
SP  - 81
EP  - 89
SN  - 2468-5739
UR  - https://doi.org/10.2991/978-94-6463-550-8_9
DO  - 10.2991/978-94-6463-550-8_9
ID  - Rosidi2024
ER  -