Study on Optimization of Extraction Method of Total Alkaloids from Zizyphi Spinosi Semen

DOI

10.2991/ifmca-16.2017.133How to use a DOI?

Keywords

Zizyphi spinosi semen, alkaloids, extract, reflux

Abstract

To obtain the best appropriate method and optimum extraction conditions of total alkaloids from Zizyphi spinosi semen (ZSS), the conditions of reflux extraction were optimized by single factor experiment and orthogonal design respectively. the experiment results were as follows: 20% acetic acid resolved in ethanol as extracting solvent ( EtOH : HAc = 80 : 20 (v/v) ), ratio of liquid to solid = 20 : 1 (ml/g), 4.0 h, 70 C, and these conditions were optimum conditions after validation of experiment. The total alkaloids of ZSS extracted by this method could provide a powerful guarantee for studying ingredients and activities of alkaloids in ZSS.

Copyright

© 2017, the Authors. Published by Atlantis Press.

Open Access

This is an open access article distributed under the CC BY-NC license (http://creativecommons.org/licenses/by-nc/4.0/).

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TY  - CONF
AU  - Yan-Zhou Hu
AU  - Ke Ding
AU  - Xiang-Ning Chen
AU  - Tao Han
PY  - 2017/03
DA  - 2017/03
TI  - Study on Optimization of Extraction Method of Total Alkaloids from Zizyphi Spinosi Semen
BT  - Proceedings of the 2016 International Forum on Mechanical, Control and Automation (IFMCA 2016)
PB  - Atlantis Press
SP  - 846
EP  - 854
SN  - 2352-5401
UR  - https://doi.org/10.2991/ifmca-16.2017.133
DO  - 10.2991/ifmca-16.2017.133
ID  - Hu2017/03
ER  -