Proceedings of the 2015 International Conference on Social Science and Technology Education

Pathological effects of the renin-angiotensin system on cardiovascular disease

Authors
Zhang Yan
Corresponding Author
Zhang Yan
Available Online April 2015.
DOI
https://doi.org/10.2991/icsste-15.2015.19How to use a DOI?
Keywords
renin - angiotensin system; angiotensin-converting enzyme 2; cardiovascular disease
Abstract

the renin -angiotensin system (RAS) found in a research as a new member, changes the past view that only the angiotensin (Ang) catalyzed by angiotensin-converting enzyme (ACE) can produce pathogenic role. The research proved the renin binding with former prime renin –receptor (RPR) and Ang binding with insulin receptor regulated aminopeptidase (IRAP) will also produce the same pathogenic role. The newly discovered ACE2 catalyzes Ang- (1-7) and Ang- (1-9) generation, then the receptor of Ang- (1-7) and Mas and the receptor of Ang- (1-9) and AT2 binding, may produce cardiovascular protective effect, but the pathogenic role of RAS is still dominant. The discovery of RAS new member provides a new theoretical basis to recognize RAS inhibitors in clinical research results.

Copyright
© 2015, the Authors. Published by Atlantis Press.
Open Access
This is an open access article distributed under the CC BY-NC license (http://creativecommons.org/licenses/by-nc/4.0/).

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Volume Title
Proceedings of the 2015 International Conference on Social Science and Technology Education
Series
Advances in Social Science, Education and Humanities Research
Publication Date
April 2015
ISBN
978-94-62520-60-8
ISSN
2352-5398
DOI
https://doi.org/10.2991/icsste-15.2015.19How to use a DOI?
Copyright
© 2015, the Authors. Published by Atlantis Press.
Open Access
This is an open access article distributed under the CC BY-NC license (http://creativecommons.org/licenses/by-nc/4.0/).

Cite this article

TY  - CONF
AU  - Zhang Yan
PY  - 2015/04
DA  - 2015/04
TI  - Pathological effects of the renin-angiotensin system on cardiovascular disease
BT  - Proceedings of the 2015 International Conference on Social Science and Technology Education
PB  - Atlantis Press
SP  - 58
EP  - 60
SN  - 2352-5398
UR  - https://doi.org/10.2991/icsste-15.2015.19
DO  - https://doi.org/10.2991/icsste-15.2015.19
ID  - Yan2015/04
ER  -