Proceedings of the 2016 International Conference on Biological Sciences and Technology

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Preparation of Diuridine and Dicytidine Pentaphosphates

Authors
Yue-Hai You, Shan-Shan Gong, Qi Sun
Corresponding Author
Yue-Hai You
Available Online January 2016.
DOI
10.2991/bst-16.2016.11How to use a DOI?
Keywords
Phosphoropiperidate, Dinucleoside pentaphosphates, Cytidine, Uridine, 4,5-dicyanoimidazole.
Abstract

Two symmetrical dinucleoside pentaphosphates, Up5U and Cp5C, were synthesized via the activation of the P (V)–N bond. The key nucleoside phosphoropiperidates intermediate were obtained by a redox condensation method. The reaction of the phosphoropiperidate with uridine and cytidine tetraphosphate in the presence of 4, 5-dicyanoimidazole (DCI) afforded the desired dinucleoside pentaphosphates in moderate isolated yields.

Copyright
© 2016, the Authors. Published by Atlantis Press.
Open Access
This is an open access article distributed under the CC BY-NC license (http://creativecommons.org/licenses/by-nc/4.0/).

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Volume Title
Proceedings of the 2016 International Conference on Biological Sciences and Technology
Series
Advances in Biological Sciences Research
Publication Date
January 2016
ISBN
978-94-6252-161-2
ISSN
2468-5747
DOI
10.2991/bst-16.2016.11How to use a DOI?
Copyright
© 2016, the Authors. Published by Atlantis Press.
Open Access
This is an open access article distributed under the CC BY-NC license (http://creativecommons.org/licenses/by-nc/4.0/).

Cite this article

risenwbib
TY  - CONF
AU  - Yue-Hai You
AU  - Shan-Shan Gong
AU  - Qi Sun
PY  - 2016/01
DA  - 2016/01
TI  - Preparation of Diuridine and Dicytidine Pentaphosphates
BT  - Proceedings of the 2016 International Conference on Biological Sciences and Technology
PB  - Atlantis Press
SP  - 62
EP  - 65
SN  - 2468-5747
UR  - https://doi.org/10.2991/bst-16.2016.11
DO  - 10.2991/bst-16.2016.11
ID  - You2016/01
ER  -