Simulations to Evaluate the Impact of Ca2+ release from Endoplasmic Reticulum on Intracellular Ca2+ Oscillations

DOI

10.2991/amms-17.2017.47How to use a DOI?

Keywords

bifurcation; calcium oscillation; fast-slow dynamic analysis

Abstract

The role of Ca2+ release from endoplasmic reticulum (ER) in influencing intracellular Ca2+ oscillation is elucidated. Various types of oscillations in a two-pool model are discussed, based on fast-slow dynamic analysis. Three types of burster are obtained by varying the parameter affecting Ca2+ release from ER, namely, subHopf-subHopf of point-cycle type, subHopf-cycle of point-cycle type with multiple rhythms and fold-fold of point-point type. The results may help us better understand the role of Ca2+ release played in complex intra- and inter-cellular Ca2+ signaling.

Copyright

© 2017, the Authors. Published by Atlantis Press.

Open Access

This is an open access article distributed under the CC BY-NC license (http://creativecommons.org/licenses/by-nc/4.0/).

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TY  - CONF
AU  - Enlin Tang
AU  - Hongkun Zuo
PY  - 2017/11
DA  - 2017/11
TI  - Simulations to Evaluate the Impact of Ca2+ release from Endoplasmic Reticulum on Intracellular Ca2+ Oscillations
BT  - Proceedings of the 2017 International Conference on Applied Mathematics, Modeling and Simulation (AMMS 2017)
PB  - Atlantis Press
SP  - 211
EP  - 214
SN  - 1951-6851
UR  - https://doi.org/10.2991/amms-17.2017.47
DO  - 10.2991/amms-17.2017.47
ID  - Tang2017/11
ER  -