Antibacterial Activity Test of Ethanol Extract of Lemongrass Leaves (Cymbopogon nardus (L.) Rendle) Against Staphylococcus epidermidis

DOI

10.2991/978-94-6463-190-6_8How to use a DOI?

Keywords

Antibacterial activity; Ethanol extract of lemongrass leaves; Staphylococcus epidermidis

Abstract

Bacterial infection is one of many people's most common health problems, especially in developing countries, including Indonesia. Staphylococcus epidermidis is one of the bacteria that causes infection. Lemongrass is a plant with several active compounds that can be use for treatment, one of which is an antibacterial. This research aimed to determine the antibacterial activity of lemongrass leaves ethanolic extract against Staphylococcus epidermidis. This type of research is a laboratory experiment using the disc diffusion method. The research stage includes making lemongrass leaves extract with variations concentrations of 5%, 10%, 20%, 40%, and 80%, phytochemical screening, and antibacterial activity testing. Data from the research were analyzed using One Way ANOVA. The results showed that the ethanol extract of Lemongrass leaves positively contained flavonoids, tannins, saponins, and essential oils. The results showed that lemongrass leaves extract had an inhibitory effect on the growth of Staphylococcus epidermidis at concentrations of 10%, 20%, 40%, and 80% with an inhibition zone diameter of 8.15 mm (moderate), 13.25 mm (substantial), 16.9 mm (concrete) and 20.6 mm (powerful), but at a concentration of 5% does not show antibacterial activity. Based on the One Way ANOVA testing results, the significance value was (p < 0.05), and the results showed a significant difference between the concentration variations of ethanolic extract lemongrass leaves against Staphylococcus epidermidis.

Copyright

© 2023 The Author(s)

Open Access

Open Access This chapter is licensed under the terms of the Creative Commons Attribution-NonCommercial 4.0 International License (http://creativecommons.org/licenses/by-nc/4.0/), which permits any noncommercial use, sharing, adaptation, distribution and reproduction in any medium or format, as long as you give appropriate credit to the original author(s) and the source, provide a link to the Creative Commons license and indicate if changes were made.

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TY  - CONF
AU  - Eni Kartika Sari
AU  - Beta Ria Erika Marita Dellima
AU  - Katarina Krisnawati Hondro
PY  - 2023
DA  - 2023/07/27
TI  - Antibacterial Activity Test of Ethanol Extract of Lemongrass Leaves (Cymbopogon nardus (L.) Rendle) Against Staphylococcus epidermidis
BT  - Proceedings of the 2022 ‘AISYIYAH International Conference on Health and Medical Sciences (A-HMS 2022)
PB  - Atlantis Press
SP  - 51
EP  - 58
SN  - 2468-5739
UR  - https://doi.org/10.2991/978-94-6463-190-6_8
DO  - 10.2991/978-94-6463-190-6_8
ID  - Sari2023
ER  -