Artery Research

Volume 12, Issue C, December 2015, Pages 19 - 19

P4.17 ARTERIAL STIFFNESS IN YOUNG PATIENTS WITH PERIPHERAL ARTERIAL DISEASE

Authors
Mariella Catalano*1, Giovanni Scandale1, Gabriel Dimitrov1, Marzio Minola1, Martino Recchia3, Francesca Galli2, Gianni Carzaniga1, Maria Carotta1
1Research Center on Vascular Diseases and Angiology Unit, University of Milan, Milan, Italy
2Laboratory of Clinical Research, Department of Oncology, IRCCS—Istituto di Ricerche Farmacologiche Mario Negri, Milan, Italy
3Medistat s.a.s, Milan, Italy
Available Online 23 November 2015.
DOI
10.1016/j.artres.2015.10.261How to use a DOI?
Abstract

Increased arterial stiffness occurs in older patients with peripheral arterial disease (PAD). In this study we compared arterial stiffness and central hemodynamic parameters in young (< 60 years of age) PAD patients and controls. In 31 PAD patients with an ankle-brachial index (ABI≤ 0.9) and 42 controls, aortic Pulse wave velocity (aPWV), Augmentation index corrected for heart rate (AIx@75HR), aortic Pulse Pressure (aPP), Pulse Pressure Amplification (PPA), were measured using the SphygmoCor device. In young PAD patients aPWV and AIx@75HR were similar (p=0.10) (p=0.58) With respect to controls but aortic PP was higher (p=0.02) and the PP amplification ratio was lower (p=0.005). PAD in young subjects is associated with central hemodynamic alterations but not with degenerative stiffness of the large arteries.

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Journal
Artery Research
Volume-Issue
12 - C
Pages
19 - 19
Publication Date
2015/11/23
ISSN (Online)
1876-4401
ISSN (Print)
1872-9312
DOI
10.1016/j.artres.2015.10.261How to use a DOI?
Open Access
This is an open access article distributed under the CC BY-NC license.

Cite this article

TY  - JOUR
AU  - Mariella Catalano*
AU  - Giovanni Scandale
AU  - Gabriel Dimitrov
AU  - Marzio Minola
AU  - Martino Recchia
AU  - Francesca Galli
AU  - Gianni Carzaniga
AU  - Maria Carotta
PY  - 2015
DA  - 2015/11/23
TI  - P4.17 ARTERIAL STIFFNESS IN YOUNG PATIENTS WITH PERIPHERAL ARTERIAL DISEASE
JO  - Artery Research
SP  - 19
EP  - 19
VL  - 12
IS  - C
SN  - 1876-4401
UR  - https://doi.org/10.1016/j.artres.2015.10.261
DO  - 10.1016/j.artres.2015.10.261
ID  - Catalano*2015
ER  -