P4.17 ARTERIAL STIFFNESS IN YOUNG PATIENTS WITH PERIPHERAL ARTERIAL DISEASE

DOI

10.1016/j.artres.2015.10.261How to use a DOI?

Abstract

Increased arterial stiffness occurs in older patients with peripheral arterial disease (PAD). In this study we compared arterial stiffness and central hemodynamic parameters in young (< 60 years of age) PAD patients and controls. In 31 PAD patients with an ankle-brachial index (ABI≤ 0.9) and 42 controls, aortic Pulse wave velocity (aPWV), Augmentation index corrected for heart rate (AIx@75HR), aortic Pulse Pressure (aPP), Pulse Pressure Amplification (PPA), were measured using the SphygmoCor device. In young PAD patients aPWV and AIx@75HR were similar (p=0.10) (p=0.58) With respect to controls but aortic PP was higher (p=0.02) and the PP amplification ratio was lower (p=0.005). PAD in young subjects is associated with central hemodynamic alterations but not with degenerative stiffness of the large arteries.

Open Access

This is an open access article distributed under the CC BY-NC license.

TY  - JOUR
AU  - Mariella Catalano*
AU  - Giovanni Scandale
AU  - Gabriel Dimitrov
AU  - Marzio Minola
AU  - Martino Recchia
AU  - Francesca Galli
AU  - Gianni Carzaniga
AU  - Maria Carotta
PY  - 2015
DA  - 2015/11/23
TI  - P4.17 ARTERIAL STIFFNESS IN YOUNG PATIENTS WITH PERIPHERAL ARTERIAL DISEASE
JO  - Artery Research
SP  - 19
EP  - 19
VL  - 12
IS  - C
SN  - 1876-4401
UR  - https://doi.org/10.1016/j.artres.2015.10.261
DO  - 10.1016/j.artres.2015.10.261
ID  - Catalano*2015
ER  -