P4.10 ASSOCIATION OF ARTERIAL STIFFNESS WITH BLOOD PRESSURE VARIABILITY

DOI

10.1016/j.artres.2015.10.254How to use a DOI?

Abstract

Increase of arterial stiffness is an independent predictor of cardiovascular morbidity and mortality. Short term blood pressure (BP) variability is recognised as a marker and a risk factor for cardiovascular complications. The study aims to determine the relation between arterial stiffness and short -term variability in general population.

Methods: We recruited 303 subjects (55.12% Female). Short-term BP variability was calculated as the standard deviation (SD) of 24-hour, daytime, or nighttime BP, and as weighted SD of 24-hour BP defined as the mean of daytime and nighttime BP SD weighted by the duration of each time period. Carotid – femoral pulse wave velocity (PWV) were evaluated by means of pulse wave analysis.

Results: In the study group the SD of day- and nighttime Systolic BP (SBP), SD of 24-hour SBP and weighted SD of 24-hour SBP showed an significant association with PWV (P<0.003). Abovementioned SBP variability indices except SD of night SBP independently predicted PWV along with age, gender, 24-hour SBP and antihypertensive treatment. None of the examined measures of diastolic BP variability had a relation with carotid-femoral PWV.

Conclusions: Short-term variability of systolic blood pressure shows an independent relation to aortic stiffness in general population. Our study confirms that those parameters are closely related.

Open Access

This is an open access article distributed under the CC BY-NC license.

TY  - JOUR
AU  - Wiktoria Wojciechowska*
AU  - Katarzyna Stolarz-Skrzypek
AU  - Agnieszka Olszanecka
AU  - Kalina Kawecka-Jaszcz
AU  - Danuta Czarnecka
PY  - 2015
DA  - 2015/11/23
TI  - P4.10 ASSOCIATION OF ARTERIAL STIFFNESS WITH BLOOD PRESSURE VARIABILITY
JO  - Artery Research
SP  - 17
EP  - 18
VL  - 12
IS  - C
SN  - 1876-4401
UR  - https://doi.org/10.1016/j.artres.2015.10.254
DO  - 10.1016/j.artres.2015.10.254
ID  - Wojciechowska*2015
ER  -