Artery Research

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Volume 4, Issue 3, September 2010, Pages 94 - 97

Effects of aging on leg pulse wave velocity response to single-leg cycling

Authors
Jun Sugawaraa, *, Takeshi Otsukib, Seiji Maedac
aHuman Life Research Institute, The National Institute of Advanced Industrial Science and Technology (AIST), Tsukuba Central 6, Tsukuba, Ibaraki 305-8566, Japan
bGraduate School of Health and Sport Sciences, Ryutsu Keizai University, Japan
cGraduate School of Comprehensive Human Sciences, University of Tsukuba, Tsukuba, Ibaraki, Japan
*Corresponding author. Tel.: +81 29 861 7138; fax: +81 29 861 6660. E-mail address: jun.sugawara@aist.go.jp (J. Sugawara).
Corresponding Author
Jun Sugawara
Received 2 June 2010, Revised 13 July 2010, Accepted 13 July 2010, Available Online 6 August 2010.
DOI
10.1016/j.artres.2010.07.002How to use a DOI?
Keywords
Arterial stiffness; Endothelial function; Aging
Abstract

There is increasing awareness that pulse wave velocity (PWV), an index of arterial stiffness, changes transiently via alteration of vascular smooth muscular tone. The aim of this study was to determine the effects of aging on the response of leg PWV to a low-intensity exercise bout. Ten older (69 ± 3 years) and 6 younger (21 ± 1 years) men were studied. Leg PWV in each subject was measured before and after a low-intensity single-leg cycling (20 W, 5 min). The younger subject group demonstrated a significant reduction in the exercised leg PWV (−8.0%) immediately after the exercise, whereas the non-exercised leg PWV did not change significantly (+2.2%). In the older subject group, no significant changes in PWV were observed in the exercised leg nor the non-exercised leg. There were no significant changes in other hemodynamic variables before or after the exercise bout in either younger or older subjects. These results indicate that the exercise-induced temporal reduction in leg arterial stiffness is blunted in older adults. The lack of exercise-induced reduction in leg PWV may be due to an age-related impairment of endothelial function.

Copyright
© 2010 Association for Research into Arterial Structure and Physiology. Published by Elsevier B.V. All rights reserved.
Open Access
This is an open access article distributed under the CC BY-NC license.

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<Previous Article In Issue
Journal
Artery Research
Volume-Issue
4 - 3
Pages
94 - 97
Publication Date
2010/08/06
ISSN (Online)
1876-4401
ISSN (Print)
1872-9312
DOI
10.1016/j.artres.2010.07.002How to use a DOI?
Copyright
© 2010 Association for Research into Arterial Structure and Physiology. Published by Elsevier B.V. All rights reserved.
Open Access
This is an open access article distributed under the CC BY-NC license.

Cite this article

risenwbib
TY  - JOUR
AU  - Jun Sugawara
AU  - Takeshi Otsuki
AU  - Seiji Maeda
PY  - 2010
DA  - 2010/08/06
TI  - Effects of aging on leg pulse wave velocity response to single-leg cycling
JO  - Artery Research
SP  - 94
EP  - 97
VL  - 4
IS  - 3
SN  - 1876-4401
UR  - https://doi.org/10.1016/j.artres.2010.07.002
DO  - 10.1016/j.artres.2010.07.002
ID  - Sugawara2010
ER  -