Oxidative stress and arterial stiffness in strength- and endurance-trained athletes

Youngju Choi; Seiji Maeda; Takeshi Otsuki; Asako Miyaki; Nobutake Shimojo; Mutsuko Yoshizawa; Hitoshi Shiraki; Ryuichi Ajisaka

doi:10.1016/j.artres.2010.04.002

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Volume 4, Issue 2, June 2010, Pages 52 - 58

Oxidative stress and arterial stiffness in strength- and endurance-trained athletes

Authors

Youngju Choi^a, Seiji Maeda^a^{, *}, Takeshi Otsuki^b, Asako Miyaki^a, Nobutake Shimojo^c, Mutsuko Yoshizawa^a, Hitoshi Shiraki^a, Ryuichi Ajisaka^a

^aDivision of Sports Medicine, Graduate School of Comprehensive Human Sciences, University of Tsukuba, Ibaraki, Japan

^bGraduate School of Health and Sport Sciences, Ryutsu Keizai University, Ibaraki, Japan

^cDivision of Cardiovascular Medicine, Graduate School of Comprehensive Human Sciences, University of Tsukuba, Ibaraki, Japan

^*Corresponding author. Tel.: +81 29 853 2683; fax: +81 29 853 2986. E-mail address: maeda@taiiku.tsukuba.ac.jp (S. Maeda).

Corresponding Author

Seiji Maeda

Received 11 February 2010, Revised 23 April 2010, Accepted 29 April 2010, Available Online 27 May 2010.

DOI: 10.1016/j.artres.2010.04.002 How to use a DOI?
Keywords: Strength training; Endurance training; Pulse-wave velocity; Arterial compliance; AOPP
Abstract: Background: Endurance exercise training decreases arterial stiffness, whereas high-intensity strength exercise training increases arterial stiffness. However, the mechanisms underlying the adaptations to the 2 types of exercise training remain unclear. Increased oxidative stress induces vasoconstriction and endothelial dysfunction. Plasma advanced oxidation protein products (AOPP)—a novel marker of oxidative stress—have recently been reported to be positively associated with arterial stiffness in healthy subjects. We hypothesized that AOPP are involved in the adaptation of arterial stiffness in different types of exercise training.

Methods: We investigated plasma AOPP concentration and arterial stiffness in strength- and endurance-trained athletes. The subjects included young strength-trained athletes (SA group) (shot put, hammer, or javelin throwers; n = 12), endurance-trained athletes (EA group) (long- or middle-distance runners; n = 10), and sedentary individuals (Control group) (n = 12). We measured aortic pulse-wave velocity (PWV), systemic arterial compliance (SAC), and plasma AOPP concentrations.

Results: PWV was higher in the SA than in the EA or control groups (SA: 6.48 ± 0.47, EA: 6.00 ± 0.67, Control: 5.65 ± 0.52 m/s, mean ± SD), and SAC was lower in the SA than in the EA or control groups (SA: 1.04 ± 0.24, EA: 1.56 ± 0.44, Control: 1.38 ± 0.35 ml/mmHg); thus, arterial stiffness was higher in the SA group. Plasma AOPP concentrations were higher in the SA group than in the EA group (SA: 31.7 ± 8.5, EA: 23.9 ± 6.9, Control: 27.2 ± 3.9 μmol/l). We found that plasma AOPP levels tended to be related to SAC (P = 0.073, r = −0.31).

Conclusions: The present study provides a possibility that exercise training-induced oxidative stress may be partly involved in the mechanism underlying the adaptation of arterial stiffness in strength- and endurance-trained athletes.
Open Access: This is an open access article distributed under the CC BY-NC license.

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Journal: Artery Research
Volume-Issue: 4 - 2
Pages: 52 - 58
Publication Date: 2010/05/27
ISSN (Online): 1876-4401
ISSN (Print): 1872-9312
DOI: 10.1016/j.artres.2010.04.002 How to use a DOI?
Open Access: This is an open access article distributed under the CC BY-NC license.

Cite this article

ris enw bib

TY  - JOUR
AU  - Youngju Choi
AU  - Seiji Maeda
AU  - Takeshi Otsuki
AU  - Asako Miyaki
AU  - Nobutake Shimojo
AU  - Mutsuko Yoshizawa
AU  - Hitoshi Shiraki
AU  - Ryuichi Ajisaka
PY  - 2010
DA  - 2010/05/27
TI  - Oxidative stress and arterial stiffness in strength- and endurance-trained athletes
JO  - Artery Research
SP  - 52
EP  - 58
VL  - 4
IS  - 2
SN  - 1876-4401
UR  - https://doi.org/10.1016/j.artres.2010.04.002
DO  - 10.1016/j.artres.2010.04.002
ID  - Choi2010
ER  -

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