Volume 2, Issue 1, February 2008, Pages 21 - 34
Identifying the vulnerable plaque: A review of invasive and non-invasive imaging modalities
Authors
Jan G. Kipsa, b, Patrick Segersa, Luc M. Van Bortelb, *
aCardiovascular Mechanics and Biofluid Dynamics, Institute Biomedical Technology, Gent University, Gent, Belgium
bHeymans Institute for Pharmacology, Gent University, Gent, Belgium
*Corresponding author. Heymans Institute for Pharmacology, Gent University, De Pintelaan 185, B-9000 Gent, Belgium. E-mail address: luc.vanbortel@ugent.be (L.M. Van Bortel).
Corresponding Author
Luc M. Van Bortel
Received 29 June 2007, Revised 21 November 2007, Accepted 27 November 2007, Available Online 25 January 2008.
- DOI
- 10.1016/j.artres.2007.11.002How to use a DOI?
- Keywords
- Atherosclerosis; Plaque; Clinical imaging; Cardiovascular disease
- Abstract
Atherosclerotic cardiovascular disease is the current leading cause of death in industrialized countries. The vast majority of acute cardiovascular events (50–70%) are ascribed to thrombosis following rupture of a vulnerable plaque. Therefore there is an urgent need to discern vulnerable, unstable plaques from stable plaques. A variety of imaging modalities, both invasive and non-invasive, have been developed for the assessment of visualization and quantification of atherosclerosis. In this review, we discuss the advantages and limitations of the available imaging techniques, and their clinical potential for assessment of plaque vulnerability.
- Copyright
- © 2007 Association for Research into Arterial Structure and Physiology. Published by Elsevier B.V. All rights reserved.
- Open Access
- This is an open access article distributed under the CC BY-NC license.
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TY - JOUR AU - Jan G. Kips AU - Patrick Segers AU - Luc M. Van Bortel PY - 2008 DA - 2008/01/25 TI - Identifying the vulnerable plaque: A review of invasive and non-invasive imaging modalities JO - Artery Research SP - 21 EP - 34 VL - 2 IS - 1 SN - 1876-4401 UR - https://doi.org/10.1016/j.artres.2007.11.002 DO - 10.1016/j.artres.2007.11.002 ID - Kips2008 ER -