Artery Research

Volume 2, Issue 1, February 2008, Pages 9 - 20

Magnetic resonance imaging in vascular biology☆

Authors
Matthias Voehringera, b, Udo Sechtemb, Matthias G. Friedricha, *
aDepartment of Cardiovascular Sciences and Stephenson CMR Centre at the Libin Cardiovascular Institute of Alberta, University of Calgary, Canada
bDepartment of Cardiology, Robert-Bosch-Krankenhaus, Stuttgart, Germany

Grant support: M. Voehringer is supported by a research scholarship of Robert-Bosch Foundation, Germany, and is a trainee in the strategic training programme TORCH of University of Calgary and University of Alberta.

*Corresponding author. Stephenson CMR Centre, Foothills Medical Centre, Suite 0700-SSB, 1403-29th ST NW, Calgary, AB, Canada T2 N-2T9. Tel.: +1 (403) 944 8600; fax: +1 (403) 944 8510. E-mail address: matthias.friedrich@ucalgary.ca (M.G. Friedrich).
Corresponding Author
Matthias G. Friedrich
Received 12 September 2007, Revised 20 November 2007, Accepted 17 January 2008, Available Online 29 February 2008.
DOI
https://doi.org/10.1016/j.artres.2008.01.002How to use a DOI?
Keywords
Magnetic resonance imaging, Atherosclerosis, Imaging, Vessels
Abstract

Symptoms are only the tip of the iceberg in atherosclerotic disease. Beneath the surface are multiple patho-physiological processes taking place in and around the vessel wall. The increasing knowledge in the field of vascular biology also reveals new imaging targets as biological markers of the disease. Promising targets particularly relate to the early detection of subjects at risk and monitoring of therapeutical efforts. Among other imaging modalities magnetic resonance imaging (MRI) is an emerging tool with strong potential and a favourable safety profile. This article summarizes the different approaches of imaging various facets of atherosclerotic disease by MRI. In particular, endothelial function, arterial stiffness, vessel remodeling, angiogenesis inside the vessel wall, vessel stenosis and plaque characterization are addressed. As such MRI is a very versatile diagnostic tool for vascular biology research with high diagnostic accuracy and reproducibility of its results. Moreover, MRI allows for comprehensive studies, applying several techniques within one exam.

Copyright
© 2008 Association for Research into Arterial Structure and Physiology. Published by Elsevier B.V. All rights reserved.
Open Access
This is an open access article distributed under the CC BY-NC license.

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Journal
Artery Research
Volume-Issue
2 - 1
Pages
9 - 20
Publication Date
2008/02
ISSN (Online)
1876-4401
ISSN (Print)
1872-9312
DOI
https://doi.org/10.1016/j.artres.2008.01.002How to use a DOI?
Copyright
© 2008 Association for Research into Arterial Structure and Physiology. Published by Elsevier B.V. All rights reserved.
Open Access
This is an open access article distributed under the CC BY-NC license.

Cite this article

TY  - JOUR
AU  - Matthias Voehringer
AU  - Udo Sechtem
AU  - Matthias G. Friedrich
PY  - 2008
DA  - 2008/02
TI  - Magnetic resonance imaging in vascular biology☆
JO  - Artery Research
SP  - 9
EP  - 20
VL  - 2
IS  - 1
SN  - 1876-4401
UR  - https://doi.org/10.1016/j.artres.2008.01.002
DO  - https://doi.org/10.1016/j.artres.2008.01.002
ID  - Voehringer2008
ER  -