Proceedings of the 7th Annual International Conference on Social Science and Contemporary Humanity Development (SSCHD 2021)

Increased Urinary L-Histidine Concentrations in Children with Obesity

Authors
Li Xie1, Wei Xie2, *, Xuejun Kang3, Zexin Cheng1
1College of Animal Science and Food Engineering, Jinling Institute of Technology, 210038, Nanjing, China
2Kebai Pharmaceutical Technology Co. Ltd, Nanjing 210044, China
3Key Laboratory of Child Development and Learning Science (Ministry of Education), School of Biological Science & Medical Engineering, Southeast University, Nanjing 210096, China
*Corresponding author. Email: xiedoctor@yeah.net
Corresponding Author
Wei Xie
Available Online 15 December 2021.
DOI
10.2991/assehr.k.211215.068How to use a DOI?
Keywords
Urinary L-Histidine; Energy intake; Children with obesity
Abstract

L-histidine plays an important role in the growth of infants and young children as well as positively improves insulin resistance through suppressed inflammation. The study aimed to investigate the relationship between L-histidine levels and obesity and evaluate the feasibility of L-histidine as an important indicator of auxiliary diagnosis for pediatric obesity. Thus, the urinary content of L-histidine from 74 children with obesity and 84 normal weight were determined and analyzed in the study. Results found that the L-histidine concentration in urine (median [interquartile range] mg/L) was 8.29 (4.42-20.70) mg/L in the children with obesity and 5.60 (2.16-14.06) mg/L in the normal-weight children (P<0.01), 5.71 (2.57-17.15) mg/L in girls and 9.92 (5.54-23.33) mg/L in boys (P<0.05). L-histidine concentration in severe obesity children were significantly higher than that of mild obesity (P<0.05). The urinary L-histidine levels were positively correlate with BMI and the mean and median of L-histidine concentration in urine increase with children’s obese levels.

Copyright
© 2021 The Authors. Published by Atlantis Press SARL.
Open Access
This is an open access article under the CC BY-NC license.

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Volume Title
Proceedings of the 7th Annual International Conference on Social Science and Contemporary Humanity Development (SSCHD 2021)
Series
Advances in Social Science, Education and Humanities Research
Publication Date
15 December 2021
ISBN
978946239-485-8
ISSN
2352-5398
DOI
10.2991/assehr.k.211215.068How to use a DOI?
Copyright
© 2021 The Authors. Published by Atlantis Press SARL.
Open Access
This is an open access article under the CC BY-NC license.

Cite this article

TY  - CONF
AU  - Li Xie
AU  - Wei Xie
AU  - Xuejun Kang
AU  - Zexin Cheng
PY  - 2021
DA  - 2021/12/15
TI  - Increased Urinary L-Histidine Concentrations in Children with Obesity
BT  - Proceedings of the 7th Annual International Conference on Social Science and Contemporary Humanity Development (SSCHD 2021)
PB  - Atlantis Press
SP  - 369
EP  - 373
SN  - 2352-5398
UR  - https://doi.org/10.2991/assehr.k.211215.068
DO  - 10.2991/assehr.k.211215.068
ID  - Xie2021
ER  -