Campesterol compound from Methanol Fraction of Brotowali (Tinospora crispa) Stem Bark

DOI

10.2991/snk-19.2019.23How to use a DOI?

Keywords

Tinospora crispa, campesterol, Menispermaceae, brotowali

Abstract

Tinospora crispa is a plant of the Menispermaceae family which is one of the endemic plants in Indonesia, commonly called as Brotowali. Tinospora crispa have been used traditionally to treat fever, diabetes, rheumatism and sinusitis. The chemical components of the plant have not been reported so far. This study is intended to know the molecular structures of isolated compound of methanol fraction from T. crispa stem bark. Extraction using maceration method with n-hexana, ethyl acetate and methanol as a solvents. The chemical structures of compounds were elucidated with spectroscopic data (IR, 1H, 13C, DEPT 135º, HMQC, HMBC, 1H-1H COSY NMR) and MS as well as compared with previously reported spectra data. Charaterization structure of isolated compound was finally identified as 24(R)-methylcholesta5-en-3 β -ol (campesterol) by the comparison of several physical and spectral data with the literature. In previously study, campesterol have anticholesterol and antiangiogenic activities.

Copyright

© 2019, the Authors. Published by Atlantis Press.

Open Access

This is an open access article distributed under the CC BY-NC license (http://creativecommons.org/licenses/by-nc/4.0/).

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TY  - CONF
AU  - Weny A. J Musa
AU  - Suleman Duengo
AU  - Ahmad Kadir Kilo
PY  - 2019/12
DA  - 2019/12
TI  - Campesterol compound from Methanol Fraction of Brotowali (Tinospora crispa) Stem Bark
BT  - Proceedings of the National Seminar on Chemistry 2019 (SNK-19)
PB  - Atlantis Press
SP  - 243
EP  - 245
SN  - 2590-3195
UR  - https://doi.org/10.2991/snk-19.2019.23
DO  - 10.2991/snk-19.2019.23
ID  - Musa2019/12
ER  -