The Difference of Albumin, Tryptophan Amino Acid and IL-17 in Several Stages of Leprosy

DOI

10.2991/phico-17.2018.7How to use a DOI?

Keywords

Leprosy; Albumin; Tryptophan Amino Acid; Interleukin-17

Abstract

Nutrition linked to multiple components, systems, and processes, including those occurring during diseases, such as infection. Leprosy can be regarded as the most infectious, transmittable and long lasting disease among all infectious diseases. There have been many researches that examine nutrition with infectious disease but only a few research examined nutritional status and leprosy. The purpose of this research was to find out the difference of protein status and IL-17 in several stages of leprosy. This was a cross sectional study and was conducted on people who live in the same house or near the leprosy patients in Brebes District, Central Java, Indonesia. There are 90 people contacts households who were eligible to be screened with the examination of IgM anti PGL-1 using ELISA. Of the 90 people who were examined, 10 of them were classified as seropositive leprosy, while the 80 others were classified as seronegative leprosy, from the 80 people who were classified as seronegative leprosy, 10 were randomly picked. Ten people who were classified as leprosy type MB also included. Mean albumin serum and tryptophan amino acid tend to decrease in several stages of leprosy, but there was no significant difference (p= 0,401 and p=0,318). IL-17 level was highest at seropositive group and lowest at seronegative group, although there was no significant difference (p=0,217). It can be concluded that although there were no correlation statistically, but albumin serum, tryptophan amino acid tend to decrease and IL-17 level was fluctuate according to the severity of leprosy.

Copyright

© 2018, the Authors. Published by Atlantis Press.

Open Access

This is an open access article distributed under the CC BY-NC license (http://creativecommons.org/licenses/by-nc/4.0/).

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TY  - CONF
AU  - Mohammad Zen Rahfiludin
AU  - Siti Fatimah
AU  - Adriyan Pramono
AU  - Diana Nur Afifah
AU  - Onny Setiani
AU  - Diana Nurhayati Affandi
PY  - 2017/12
DA  - 2017/12
TI  - The Difference of Albumin, Tryptophan Amino Acid and IL-17 in Several Stages of Leprosy
BT  - Proceedings of the 2nd Public Health International Conference (PHICo 2017)
PB  - Atlantis Press
SP  - 29
EP  - 31
SN  - 2468-5739
UR  - https://doi.org/10.2991/phico-17.2018.7
DO  - 10.2991/phico-17.2018.7
ID  - ZenRahfiludin2017/12
ER  -