The Potential of Papaya Leaf Extract to Reduce Malondialdehyde Levels in the Gastric Organ of Wistar Rats Given to Used Cooking Oil

DOI

10.2991/978-94-6463-457-0_17How to use a DOI?

Keywords

Malondialdehyde; Used Cooking Oil; Papaya Leaf; Wistar Rats; Gastric organ

Abstract

Indonesian people use cooking oil extensively in food processing. Free radicals created when cooking oil is repeatedly heated to high temperatures. Oxidative stress is a result of free radical formation in tissues or cells. By Malondialdehyde (MDA), the degree of oxidative stress can be determined. Antioxidants are necessary in order to minimize oxidative damage. Papaya leaves (Carrica papaya L.), containing tannin, alkaloid, terpenoid, saponin, and flavonoid compounds, are one natural ingredient that may reduce free radicals. The purpose of this study is to compare the amounts of MDA in the gastric organs of Wistar rats that were treated with papaya leaf extract and exposed with used cooking oil. The method of this study is using a visible spectrophotometer to measure MDA levels. The initial MDA levels in the gastric organs of Wistar rats were measured at 16.5987 mg/kg before giving them of papaya leaf extract in the control group. After papaya leaf extract treatment, it was determined that the extract decrease MDA levels in the gastric organs of Wistar rats. The rats that received the treatment showed the greatest reduction in MDA levels following the consumption of 110 mg/200 g body weight of papaya leaf extract, which could lower MDA levels by as much as 71%. This result suggest that papaya leaf extract have the ability to reduce MDA levels in the gastric organs of rats.

Copyright

© 2024 The Author(s)

Open Access

Open Access This chapter is licensed under the terms of the Creative Commons Attribution-NonCommercial 4.0 International License (http://creativecommons.org/licenses/by-nc/4.0/), which permits any noncommercial use, sharing, adaptation, distribution and reproduction in any medium or format, as long as you give appropriate credit to the original author(s) and the source, provide a link to the Creative Commons license and indicate if changes were made.

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TY  - CONF
AU  - Andi Astri Kamal
AU  - Fandhi Adi Wardoyo
AU  - Ana Hidayati Mukaromah
AU  - Stalis Norma Ethica
PY  - 2024
DA  - 2024/07/22
TI  - The Potential of Papaya Leaf Extract to Reduce Malondialdehyde Levels in the Gastric Organ of Wistar Rats Given to Used Cooking Oil
BT  - Proceedings of the 2nd Lawang Sewu International Symposium on Health Sciences: Medical Laboratory Technology (LSISHS-MLT 2023)
PB  - Atlantis Press
SP  - 142
EP  - 151
SN  - 2468-5747
UR  - https://doi.org/10.2991/978-94-6463-457-0_17
DO  - 10.2991/978-94-6463-457-0_17
ID  - Kamal2024
ER  -