Changes in the Network Eigen Entropy of resting-state functional brains across the lifespan

DOI

10.2991/iwmecs-15.2015.168How to use a DOI?

Keywords

network eigen entropy (NEE),brain networks, fMRI, eigenvector centrality, graph theory.

Abstract

The brain is a dynamic and complex network formed by hierarchical interconnections among functional regions and neural systems across lifespan. Recent studies using graph theory explore the functional organization of resting-state brains have coherently indicated many non-random topological properties such as modular structure, central communication hubs, small-world property, scale-free network, and efficient network architecture. However these studies have focused mainly on partial brain attributes rather than integrated communication across brain regions and the organization or order of the brain. In this study, we explored the entire lifespan trajectory of human whole-brain organization used resting-state functional magnetic resonance imaging (rs-fMRI) and entropy analyses of graphic network. We found that the network eigen entropy (NEE) decreased from child to early middle aged but remained stable from middle aged to early old. Further, the slightly increased NEE was observed in the older people. Our findings not only revealed the U-shaped development and aging trajectory of functional organization in resting-state human that underpin variance in cognitive functions of brains across lifespan.

Copyright

© 2015, the Authors. Published by Atlantis Press.

Open Access

This is an open access article distributed under the CC BY-NC license (http://creativecommons.org/licenses/by-nc/4.0/).

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TY  - CONF
AU  - Yiming Fan
AU  - Hui Shen
AU  - Ling-li Zeng
AU  - Jian Qin
AU  - Zhiguo Luo
AU  - Dewen Hu
PY  - 2015/10
DA  - 2015/10
TI  - Changes in the Network Eigen Entropy of resting-state functional brains across the lifespan
BT  - Proceedings of the 2015 2nd International Workshop on Materials Engineering and Computer Sciences
PB  - Atlantis Press
SP  - 854
EP  - 860
SN  - 2352-538X
UR  - https://doi.org/10.2991/iwmecs-15.2015.168
DO  - 10.2991/iwmecs-15.2015.168
ID  - Fan2015/10
ER  -