Quantitative detection of MMP-2 and relationship of the clinical features and prognosis of lung cancer
- 10.2991/icsste-15.2015.54How to use a DOI?
- lung cancer, MMP-2, gene expression, invasion and metastasis, flow cytometry.
Objective is to discuss (MMP-2) relationship of matrix metalloproteinase-2 and lung cancer invasion, metastasis and prognosis. Methods: use flow immunoassay for the quantitative detection of MMP-2 expression in 28 cases of benign lung lesions and 78 cases of lung cancer. Results: MMP 2-expression promotes lung cancer is higher than benign lesions (p <0.05), and there is a significant correlation (p <0.05) of lung cancer clinical stage and histological grade. Conclusion: The high expression of MMP-2 promotes the invasion and metastasis of lung cancer is, the higher the value is, the higher the clinical stage is, and the lower the tissue differentiation is, suggesting that MMP-2 not only can be used as indicators of lung cancer, but also is effective prognosis.
- © 2015, the Authors. Published by Atlantis Press.
- Open Access
- This is an open access article distributed under the CC BY-NC license (http://creativecommons.org/licenses/by-nc/4.0/).
Cite this article
TY - CONF AU - Ma Jie AU - Peng Haiyuan AU - Peng Haiping AU - Zhu Huifang PY - 2015/04 DA - 2015/04 TI - Quantitative detection of MMP-2 and relationship of the clinical features and prognosis of lung cancer BT - Proceedings of the 2015 International Conference on Social Science and Technology Education PB - Atlantis Press SP - 183 EP - 185 SN - 2352-5398 UR - https://doi.org/10.2991/icsste-15.2015.54 DO - 10.2991/icsste-15.2015.54 ID - Jie2015/04 ER -