Surface molecular imprinted electrochemical sensor for lysozyme based on metal coordinate technology
- DOI
- 10.2991/icmea-17.2018.11How to use a DOI?
- Keywords
- electrochemical sensor; metal coordinate technology;lysozyme; electro-polymerization
- Abstract
A novel and efficient molecular imprinted polymers (MIPs) electrochemical sensor based on metal coordination technology was prepared by electro-polymerization, which was applied as a molecular recognition element to modify glassy carbon electrode (GCE) to construct an electrochemical sensor (MIPs/IDA/GR/GCE) for sensitive detection of lysozyme (Lyz). The prepared MIPs/IDA/GR/GCE showed a fast rebinding dynamics, which was successfully applied to Lyz detection with a wide linear range from 1.0 � 10-11 to 1.0 � 10-5 g/L (R=0.998) and a detection limit of 2.3 � 10-12 g/L. Moreover, the fabricated sensor possessed a good selectivity and sensitivity, providing a promising tool for immunoassays and clinical applications.
- Copyright
- © 2018, the Authors. Published by Atlantis Press.
- Open Access
- This is an open access article distributed under the CC BY-NC license (http://creativecommons.org/licenses/by-nc/4.0/).
Cite this article
TY - CONF AU - Zhonghe Chen AU - Mingbo Bao AU - Yuchuan Li AU - Zhi Chen PY - 2018/02 DA - 2018/02 TI - Surface molecular imprinted electrochemical sensor for lysozyme based on metal coordinate technology BT - Proceedings of the 4th Annual International Conference on Material Engineering and Application (ICMEA 2017) PB - Atlantis Press SP - 46 EP - 49 SN - 2352-5401 UR - https://doi.org/10.2991/icmea-17.2018.11 DO - 10.2991/icmea-17.2018.11 ID - Chen2018/02 ER -