Surface molecular imprinted electrochemical sensor for lysozyme based on metal coordinate technology

DOI

10.2991/icmea-17.2018.11How to use a DOI?

Keywords

electrochemical sensor; metal coordinate technology;lysozyme; electro-polymerization

Abstract

A novel and efficient molecular imprinted polymers (MIPs) electrochemical sensor based on metal coordination technology was prepared by electro-polymerization, which was applied as a molecular recognition element to modify glassy carbon electrode (GCE) to construct an electrochemical sensor (MIPs/IDA/GR/GCE) for sensitive detection of lysozyme (Lyz). The prepared MIPs/IDA/GR/GCE showed a fast rebinding dynamics, which was successfully applied to Lyz detection with a wide linear range from 1.0 � 10-11 to 1.0 � 10-5 g/L (R=0.998) and a detection limit of 2.3 � 10-12 g/L. Moreover, the fabricated sensor possessed a good selectivity and sensitivity, providing a promising tool for immunoassays and clinical applications.

Copyright

© 2018, the Authors. Published by Atlantis Press.

Open Access

This is an open access article distributed under the CC BY-NC license (http://creativecommons.org/licenses/by-nc/4.0/).

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TY  - CONF
AU  - Zhonghe Chen
AU  - Mingbo Bao
AU  - Yuchuan Li
AU  - Zhi Chen
PY  - 2018/02
DA  - 2018/02
TI  - Surface molecular imprinted electrochemical sensor for lysozyme based on metal coordinate technology
BT  - Proceedings of the 4th Annual International Conference on Material Engineering and Application (ICMEA 2017)
PB  - Atlantis Press
SP  - 46
EP  - 49
SN  - 2352-5401
UR  - https://doi.org/10.2991/icmea-17.2018.11
DO  - 10.2991/icmea-17.2018.11
ID  - Chen2018/02
ER  -