Proceedings of the International Conference on Health and Well-Being (ICHWB 2021)

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Protective Effect of Green Tea Extract on Leptin and Lipid Profile Levels as Result of Induction of Depot Medroxyprogesterone Acetate

Authors
Endang Sri Wahyuni1, *, Maryatun Maryatun2, Nora Veri3, Elly Susilawati4, Lely Firrahmawati5, Endah Sri Wahyuni6
1Midwifery Study Program, Universitas Aisyiyah Surakarta, Central of Java, Indonesia
2Nursing Studi Program, Universitas Aisyiyah Surakarta, Central of Java, Indonesia
3Midwifery Study Program, Ministry of Health Polytechnic of Langsa, Aceh, Special Region of Aceh, Indonesia
4Department of Midwifery, Polytechnic of Health, Ministry of Health, Riau, Indonesia
5Midwifery Study Program, Universitas Aisyiyah Surakarta, Central of Java, Indonesia
6Nursing Studi Program, Universitas Aisyiyah Surakarta, Central of Java, Indonesia
*Corresponding author. Email: endang@aiska-university.ac.id
Corresponding Author
Endang Sri Wahyuni
Available Online 13 April 2022.
DOI
10.2991/ahsr.k.220403.009How to use a DOI?
Keywords
Catechin; Contraception; Lipid metabolism; Tea; Weight
Abstract

Objective: The purpose of this study was to investigate the effects of administration of green tea extract in reducing visceral fat, leptin level, and improvement of lipid profile in female rats injected with depot medroxyprogesterone acetate (DMPA). Material and methods: A total of thirty Rattus norvegicus rats were divided into five groups (n=6), consisting of control group (without treatment), group receiving DMPA injection, and group receiving DMPA injection and administration of various doses of green tea extract. Fat tissues were weighed by Ohaus scale. Leptin analysis was done by ELISA technique. Analysis of HDL and LDL levels was performed by spectrophotometry. Results: DMPA induced the increase in leptin level significantly compared with control group (p<0.05). This increase can be reduced by all doses of green tea extract, even reaching a value equal to control group for both highest doses (p>0.05). DMPA significantly increased LDL level compared with control group (p<0.05), and can be restored by control group level by administration of the highest green tea extract dose. DMPA triggered a decrease in HDL level significantly compare to the control group (p<0.05). Management of first green tea extract dose can achieve HDL level equal to control group (p>0.05). Conclusions: It was concluded that green tea extract can protect metabolic status through decreased leptin and improvement of lipid profile induced by DMPA.

Copyright
© 2022 The Authors. Published by Atlantis Press International B.V.
Open Access
This is an open access article distributed under the CC BY-NC 4.0 license.

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Volume Title
Proceedings of the International Conference on Health and Well-Being (ICHWB 2021)
Series
Advances in Health Sciences Research
Publication Date
13 April 2022
ISBN
10.2991/ahsr.k.220403.009
ISSN
2468-5739
DOI
10.2991/ahsr.k.220403.009How to use a DOI?
Copyright
© 2022 The Authors. Published by Atlantis Press International B.V.
Open Access
This is an open access article distributed under the CC BY-NC 4.0 license.

Cite this article

risenwbib
TY  - CONF
AU  - Endang Sri Wahyuni
AU  - Maryatun Maryatun
AU  - Nora Veri
AU  - Elly Susilawati
AU  - Lely Firrahmawati
AU  - Endah Sri Wahyuni
PY  - 2022
DA  - 2022/04/13
TI  - Protective Effect of Green Tea Extract on Leptin and Lipid Profile Levels as Result of Induction of Depot Medroxyprogesterone Acetate
BT  - Proceedings of the International Conference on Health and Well-Being (ICHWB 2021)
PB  - Atlantis Press
SP  - 65
EP  - 69
SN  - 2468-5739
UR  - https://doi.org/10.2991/ahsr.k.220403.009
DO  - 10.2991/ahsr.k.220403.009
ID  - Wahyuni2022
ER  -