An Overview of TSE Diseases
- DOI
- 10.2991/978-2-494069-89-3_190How to use a DOI?
- Keywords
- TSE disease; Misfolded; Prion protein; Detect; Therapeutics
- Abstract
Prion disease is a sparse, life threatening, and unusually dramatic neurodegenerative disease. Although there is no radical cure for prion diseases, the diseases follow an apparent pathogenic mechanism. A single gene produces a single corresponding prion protein (pRP) that could potentially transform into the only disease-causing factor, a misfolded prion. The cellular prion protein PrP C is a small glycoprotein on the cellular surface whose roles is currently unknown. Besides that, it is a critical molecule associated with a school of neurodegenerative diseases known as infectious spongiform encephalopathies (also known as prion diseases). Currently, the definitive diagnosis of TSE is determined post-mortem and is difficult to detect in asymptomatic carriers of the disease. There is a greatneed for improved methods to detect TSE to improve the safety of food, drugs, and blood products.
- Copyright
- © 2022 The Author(s)
- Open Access
- Open Access This chapter is licensed under the terms of the Creative Commons Attribution-NonCommercial 4.0 International License (http://creativecommons.org/licenses/by-nc/4.0/), which permits any noncommercial use, sharing, adaptation, distribution and reproduction in any medium or format, as long as you give appropriate credit to the original author(s) and the source, provide a link to the Creative Commons license and indicate if changes were made.
Cite this article
TY - CONF AU - Houhua Hu PY - 2022 DA - 2022/12/30 TI - An Overview of TSE Diseases BT - Proceedings of the 2022 5th International Conference on Humanities Education and Social Sciences (ICHESS 2022) PB - Atlantis Press SP - 1656 EP - 1662 SN - 2352-5398 UR - https://doi.org/10.2991/978-2-494069-89-3_190 DO - 10.2991/978-2-494069-89-3_190 ID - Hu2022 ER -