Proceedings of the 2022 5th International Conference on Humanities Education and Social Sciences (ICHESS 2022)

An Overview of TSE Diseases

Authors
Houhua Hu1, *
1The Pennsylvania State University, Pennsylvania, United States
*Corresponding author. Email: hqh5298@psu.edu
Corresponding Author
Houhua Hu
Available Online 30 December 2022.
DOI
10.2991/978-2-494069-89-3_190How to use a DOI?
Keywords
TSE disease; Misfolded; Prion protein; Detect; Therapeutics
Abstract

Prion disease is a sparse, life threatening, and unusually dramatic neurodegenerative disease. Although there is no radical cure for prion diseases, the diseases follow an apparent pathogenic mechanism. A single gene produces a single corresponding prion protein (pRP) that could potentially transform into the only disease-causing factor, a misfolded prion. The cellular prion protein PrP C is a small glycoprotein on the cellular surface whose roles is currently unknown. Besides that, it is a critical molecule associated with a school of neurodegenerative diseases known as infectious spongiform encephalopathies (also known as prion diseases). Currently, the definitive diagnosis of TSE is determined post-mortem and is difficult to detect in asymptomatic carriers of the disease. There is a greatneed for improved methods to detect TSE to improve the safety of food, drugs, and blood products.

Copyright
© 2022 The Author(s)
Open Access
Open Access This chapter is licensed under the terms of the Creative Commons Attribution-NonCommercial 4.0 International License (http://creativecommons.org/licenses/by-nc/4.0/), which permits any noncommercial use, sharing, adaptation, distribution and reproduction in any medium or format, as long as you give appropriate credit to the original author(s) and the source, provide a link to the Creative Commons license and indicate if changes were made.

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Volume Title
Proceedings of the 2022 5th International Conference on Humanities Education and Social Sciences (ICHESS 2022)
Series
Advances in Social Science, Education and Humanities Research
Publication Date
30 December 2022
ISBN
978-2-494069-89-3
ISSN
2352-5398
DOI
10.2991/978-2-494069-89-3_190How to use a DOI?
Copyright
© 2022 The Author(s)
Open Access
Open Access This chapter is licensed under the terms of the Creative Commons Attribution-NonCommercial 4.0 International License (http://creativecommons.org/licenses/by-nc/4.0/), which permits any noncommercial use, sharing, adaptation, distribution and reproduction in any medium or format, as long as you give appropriate credit to the original author(s) and the source, provide a link to the Creative Commons license and indicate if changes were made.

Cite this article

TY  - CONF
AU  - Houhua Hu
PY  - 2022
DA  - 2022/12/30
TI  - An Overview of TSE Diseases
BT  - Proceedings of the 2022 5th International Conference on Humanities Education and Social Sciences (ICHESS 2022)
PB  - Atlantis Press
SP  - 1656
EP  - 1662
SN  - 2352-5398
UR  - https://doi.org/10.2991/978-2-494069-89-3_190
DO  - 10.2991/978-2-494069-89-3_190
ID  - Hu2022
ER  -