A novel far-red fluorescence bioimaging probe based on rhodamine 101 derivative for Cu2+ with high sensitivity and selectivity
Authors
Zhi-Xiang Han, Chun-Liu Wang, Tong-Liang Wu, Yong-Lai Xue
Corresponding Author
Zhi-Xiang Han
Available Online January 2016.
- DOI
- 10.2991/iccte-16.2016.194How to use a DOI?
- Keywords
- Rhodamine 101; Cu2+; Fluorescent imaging; Living cells
- Abstract
A novel rhodamine 101 derivative has been synthesized and employed as a fluorescent off-on probe for monitoring Cu2+ in aqueous solutions and living cells. Under physiological conditions, it exhibits a remarkable increase in absorbance at 587 nm and an enhanced fluorescence at 615 nm toward Cu2+ in a highly sensitive, selective and rapid manner. The probe can be applied to the quantification of Cu2+ with a linear concentration range covering from 0.4 M to 16 M (R2 = 0.9955) and a detection limit of 40 nM. Furthermore, the proposed probe has been successfully applied for fluorescence imaging of Cu2+ in living cells.
- Copyright
- © 2016, the Authors. Published by Atlantis Press.
- Open Access
- This is an open access article distributed under the CC BY-NC license (http://creativecommons.org/licenses/by-nc/4.0/).
Cite this article
TY - CONF AU - Zhi-Xiang Han AU - Chun-Liu Wang AU - Tong-Liang Wu AU - Yong-Lai Xue PY - 2016/01 DA - 2016/01 TI - A novel far-red fluorescence bioimaging probe based on rhodamine 101 derivative for Cu2+ with high sensitivity and selectivity BT - Proceedings of the 2016 International Conference on Civil, Transportation and Environment PB - Atlantis Press SP - 1111 EP - 1114 SN - 2352-5401 UR - https://doi.org/10.2991/iccte-16.2016.194 DO - 10.2991/iccte-16.2016.194 ID - Han2016/01 ER -