Immunostimulant Effect of Peronema canescens. Jack Leaves Extract and Propolis in Male White Mice

DOI

10.2991/ahsr.k.211105.038How to use a DOI?

Keywords

immunostimulant; Peronema canescens; carbon clearance; leucocyte cells

Abstract

Peronema canescens leaves are one of the natural ingredients that have the potential to increase the immune system. This study determine the immunostimulant effect which identify the effectiveness of phagocytosis in killing pathogens using the carbon clearance method. The parameters that used in this study were the number of leukocyte cells. Thirty male mice used in this study which randomly divided into six groups. First group is given Na CMC 0.5% as negative control. The second group is given propolis 195 mg/kgBW as comparison group. The third group is given suspension extract 10 mg/kg BW. The fourth group is given extract suspension 50 mg/kg BW. The fifth group is given extract suspension 100 mg/kg BW. Whereas, the sixth group is given extract suspension 200 mg/kg BW. All of groups were treated for seven days and on the 8th day the mice were euthanized and their blood was taken to observe the leukocyte cells and then the tails were injected with carbon intravenously. The data were analyzed statistically with ANOVA. The result shows a significant difference (p<0.05) against the negative control group in carbon clereance and the total number of leukocytes in male white mice. It can be concluded that there is an immunostimulatory effect on the ethanol extract of sungkai leaves (Peronema canescens. Jack) in male white mice.

Copyright

© 2021 The Authors. Published by Atlantis Press International B.V.

Open Access

This is an open access article under the CC BY-NC license.

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TY  - CONF
AU  - Dwisari Dillasamola
AU  - Syofyan
AU  - Almahdy
AU  - Fitri Rachmaini
AU  - Mila Yultri
AU  - Hanifatul Larisa
AU  - Elsya Gustia
AU  - Skunda Diliarosta
AU  - Biomechy Oktomalioputri
PY  - 2021
DA  - 2021/11/17
TI  - Immunostimulant Effect of Peronema canescens. Jack Leaves Extract and Propolis in Male White Mice
BT  - Proceedings of the 2nd International Conference on Contemporary Science and Clinical Pharmacy 2021 (ICCSCP 2021)
PB  - Atlantis Press
SP  - 262
EP  - 267
SN  - 2468-5739
UR  - https://doi.org/10.2991/ahsr.k.211105.038
DO  - 10.2991/ahsr.k.211105.038
ID  - Dillasamola2021
ER  -