Identification of Expressed, Mutated Genes and Binding Sites of DNA Associated Proteins in Alzheimer’s Disease

V. Maruthi Raj; Preenon Bagchi

doi:10.2991/978-94-6463-164-7_5

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Identification of Expressed, Mutated Genes and Binding Sites of DNA Associated Proteins in Alzheimer’s Disease

Authors

V. Maruthi Raj²^{, *}, Preenon Bagchi¹^{, 2}^{, 3}

¹Padmashree Institute of Management and Science, Bangalore, India

²Vasishth Academy of Advanced Studies and Research (Sarvasumana Association), Bangalore, India

³MGM Institute of Biosciences and Technology, Aurangabad, India

^*Corresponding author. Email: maruthi1206@gmail.com

Corresponding Author

V. Maruthi Raj

Available Online 5 June 2023.

DOI: 10.2991/978-94-6463-164-7_5 How to use a DOI?
Keywords: Alzheimer’s disease (AD); neurodegeneration; transcriptomics; amyloid; Presenilin
Abstract: Background: A neurodegenerative disorder in the elderly individuals. It is a type of dementia that affects memory subsequently followed by executive dysfunction, confusion, agitation, and behavioral disturbances. Three causative genes have been associated with autosomal dominant familial AD (APP, PSEN1, and PSEN2). Identification of these genes has led to a number of animal models that have been useful to study the pathogenesis underlying AD. The primary goal of this study is to identify a set of biomarkers that maximise prediction performance in the blood and could aid in the early detection of Alzheimer’s disease as well as provide valuable information about the molecular mechanisms that underpin Alzheimer’s disease.
Copyright: © 2023 The Author(s)
Open Access: Open Access This chapter is licensed under the terms of the Creative Commons Attribution-NonCommercial 4.0 International License (http://creativecommons.org/licenses/by-nc/4.0/), which permits any noncommercial use, sharing, adaptation, distribution and reproduction in any medium or format, as long as you give appropriate credit to the original author(s) and the source, provide a link to the Creative Commons license and indicate if changes were made.

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Volume Title: Proceedings of the Joint 3rd International Conference on Bioinformatics and Data Science (ICBDS 2022)
Series: Advances in Health Sciences Research
Publication Date: 5 June 2023
ISBN: 10.2991/978-94-6463-164-7_5
ISSN: 2468-5739
DOI: 10.2991/978-94-6463-164-7_5 How to use a DOI?
Open Access: Open Access This chapter is licensed under the terms of the Creative Commons Attribution-NonCommercial 4.0 International License (http://creativecommons.org/licenses/by-nc/4.0/), which permits any noncommercial use, sharing, adaptation, distribution and reproduction in any medium or format, as long as you give appropriate credit to the original author(s) and the source, provide a link to the Creative Commons license and indicate if changes were made.

Cite this article

ris enw bib

TY  - CONF
AU  - V. Maruthi Raj
AU  - Preenon Bagchi
PY  - 2023
DA  - 2023/06/05
TI  - Identification of Expressed, Mutated Genes and Binding Sites of DNA Associated Proteins in Alzheimer’s Disease
BT  - Proceedings of the Joint 3rd International Conference on Bioinformatics and Data Science (ICBDS 2022)
PB  - Atlantis Press
SP  - 50
EP  - 64
SN  - 2468-5739
UR  - https://doi.org/10.2991/978-94-6463-164-7_5
DO  - 10.2991/978-94-6463-164-7_5
ID  - Raj2023
ER  -

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