Study on Purification of Chlorogenic Acid from Flos Lonicera Japonicae by Ionic Liquid Modified Macroporous Resin
- DOI
- 10.2991/icammce-18.2018.9How to use a DOI?
- Keywords
- Flos Lonicera Japonicae, Chlorogenic Acid, Ionic liquids, Macroporous resin, Purification
- Abstract
Ionic liquids (ILs) were used to modify macroporous resins (MARs) to purify chlorogenic acid (CGA) with Flos Lonicera Japonicae (FLJ) extract as raw material. By comparing the static adsorption and desorption effects of four MARS, the NKA-2 resin was determined as the best purification material. The NKA-2 resin was modified by ILs to obtain the modified resin NKA-2-IL and its structure was characterized by infrared spectroscopy. The optimum conditions for the purification of NKA-2-IL MARS were investigated by single-factor experiments: sample concentration was 0.25 mg/mL, eluent was 70% (v/v) ethanol, solution pH was 3.0, sample speed was 0.4 mL/min, elution rate was 0.6 mL/min and aspect ratio was 30: 1. Under this condition, the purity of CGA increased from 5.13% to 69.08%, CGA yield was 89.5% and the purity of isochlorogenic acid (ICGA) was 22.12%. The results showed that the purification of CGA by NKA-2-IL MARS was significantly improved compared with that reported in the literature.
- Copyright
- © 2018, the Authors. Published by Atlantis Press.
- Open Access
- This is an open access article distributed under the CC BY-NC license (http://creativecommons.org/licenses/by-nc/4.0/).
Cite this article
TY - CONF AU - Yang Sun AU - Hongyue Chen AU - Chao Xu AU - Ding Song AU - Yi Hu PY - 2018/05 DA - 2018/05 TI - Study on Purification of Chlorogenic Acid from Flos Lonicera Japonicae by Ionic Liquid Modified Macroporous Resin BT - Proceedings of the 2018 3rd International Conference on Advances in Materials, Mechatronics and Civil Engineering (ICAMMCE 2018) PB - Atlantis Press SP - 43 EP - 47 SN - 2352-5401 UR - https://doi.org/10.2991/icammce-18.2018.9 DO - 10.2991/icammce-18.2018.9 ID - Sun2018/05 ER -