An electrochemical codeine sensor based on CdS nanparticle label

DOI

10.2991/icadme-15.2015.319How to use a DOI?

Keywords

Electrochemical sensor, codeine, CdS nanoparticles, aptamer

Abstract

In the present study, we describe an electrochemical sensor for codeine detection by using the DNA aptamers against codeine. In the sensing protocol, a dually-labeled DNA Aptamer probe was designed to be labeled at one end with HS, and at its another end with an dabcyl as an electrochemical tag to produce electrochemical signal from recongization occurrence. One special electrochemical marker was prepared by modifying CdS nanoparticle with b-cyclodextrins (ab. CdS-CDs), which employed as electrochemical signal provider and would conjunct with the thrombin probe modified electrode through the host–guest recognition of CDs to dabcyl. With codeine adding, aptamer folding allows the CdS-CDs into soultion which caused a increased current signal. This sensor have the ability to detect 27pM codeine.

Copyright

© 2015, the Authors. Published by Atlantis Press.

Open Access

This is an open access article distributed under the CC BY-NC license (http://creativecommons.org/licenses/by-nc/4.0/).

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TY  - CONF
AU  - Wei Xiong
AU  - Sufang Wu
AU  - Fusheng Liao
AU  - Nian Hong
AU  - Hao Fan
PY  - 2015/10
DA  - 2015/10
TI  - An electrochemical codeine sensor based on CdS nanparticle label
BT  - Proceedings of the 5th International Conference on Advanced Design and Manufacturing Engineering
PB  - Atlantis Press
SP  - 1729
EP  - 1732
SN  - 2352-5401
UR  - https://doi.org/10.2991/icadme-15.2015.319
DO  - 10.2991/icadme-15.2015.319
ID  - Xiong2015/10
ER  -