An electrochemical codeine sensor based on CdS nanparticle label
- https://doi.org/10.2991/icadme-15.2015.319How to use a DOI?
- Electrochemical sensor, codeine, CdS nanoparticles, aptamer
In the present study, we describe an electrochemical sensor for codeine detection by using the DNA aptamers against codeine. In the sensing protocol, a dually-labeled DNA Aptamer probe was designed to be labeled at one end with HS, and at its another end with an dabcyl as an electrochemical tag to produce electrochemical signal from recongization occurrence. One special electrochemical marker was prepared by modifying CdS nanoparticle with b-cyclodextrins (ab. CdS-CDs), which employed as electrochemical signal provider and would conjunct with the thrombin probe modified electrode through the host–guest recognition of CDs to dabcyl. With codeine adding, aptamer folding allows the CdS-CDs into soultion which caused a increased current signal. This sensor have the ability to detect 27pM codeine.
- © 2015, the Authors. Published by Atlantis Press.
- Open Access
- This is an open access article distributed under the CC BY-NC license (http://creativecommons.org/licenses/by-nc/4.0/).
Cite this article
TY - CONF AU - Wei Xiong AU - Sufang Wu AU - Fusheng Liao AU - Nian Hong AU - Hao Fan PY - 2015/10 DA - 2015/10 TI - An electrochemical codeine sensor based on CdS nanparticle label BT - Proceedings of the 5th International Conference on Advanced Design and Manufacturing Engineering PB - Atlantis Press SP - 1729 EP - 1732 SN - 2352-5401 UR - https://doi.org/10.2991/icadme-15.2015.319 DO - https://doi.org/10.2991/icadme-15.2015.319 ID - Xiong2015/10 ER -