The Effects of Human Albumin, Normal Saline and Jambi’s Honey as Anti-Adhesive Agent in Laparotomized Rats

DOI

10.2991/aer.k.210825.050How to use a DOI?

Keywords

Adhesion, Human Albumin, Normal Saline, Honey, Laparotomy, Rats

Abstract

Postoperative peritoneal adhesion formation after surgery is result of peritoneal surface trauma and tissue ischemia. anti-adhesive agent is one of methods to reduce tissue adhesion. Honey has a long history medicine as anti-inflammatory, anti-bacterial and wound healing agent. Thirty-six healthy male wistar rats divide into six group. Control group as group A, normal saline as group B, minimal dose of honey as Group C, maximal dose of honey as group D, minimal dose of human albumin as group E and maximal dose of Human Albumin as Group F. the identification Adhesio in macroscopic based on PAI score. The microscopic based on inflammatory cell and, fibroblast cell was assessed after 10 days. the comparison in two group based on PAI was significant in group Avs C (p value: 0.02), A Vs D (p-value:.04), AVs E (p-value:.04) and AVs F (p-value:.04), but in all groups was not significant in microscopic appearance. Jambi’s honey and Human Albumin has an anti-adhesive effect in clean wound without contaminated.

Copyright

© 2021, the Authors. Published by Atlantis Press.

Open Access

This is an open access article distributed under the CC BY-NC license (http://creativecommons.org/licenses/by-nc/4.0/).

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TY  - CONF
AU  - Miftahurrahmah
AU  - Marpaung Willy
AU  - Tan Reza Ade
AU  - Anati Purwakanthi
AU  - Indah Esa
PY  - 2021
DA  - 2021/08/26
TI  - The Effects of Human Albumin, Normal Saline and Jambi’s Honey as Anti-Adhesive Agent in Laparotomized Rats
BT  - Proceedings of the 3rd Green Development International Conference (GDIC 2020)
PB  - Atlantis Press
SP  - 281
EP  - 283
SN  - 2352-5401
UR  - https://doi.org/10.2991/aer.k.210825.050
DO  - 10.2991/aer.k.210825.050
ID  - 2021
ER  -