Research on Modular Construction of Gene Regulatory Network

DOI

10.2991/emcs-17.2017.171How to use a DOI?

Keywords

Gene regulatory network; Network motif; Network construction; Modular construction

Abstract

Gene regulatory network is a large number of genes regulated by transcriptional factors and translated into protein complex information so as to realize the biological function, is an important part of people's understanding of biological processes and gene function. In order to understand the regulatory mechanism of gene regulatory networks, the network topology and its organization is one of the most important research contents. It can not only describe the local characteristics of the network, but also can reveal the construction method of the control network. The control network can be divided into 4 layers: control elements, Motif, modules and the whole network. At present, more and more people have recognized the hierarchy. Motif and two key module is discussed in this article are compared and analyzed in recent years on many aspects of the research content of network organization structure, expounds the biological significance of various research results and conclusion have, and pointed out the existing problems. On this basis, the paper also puts forward the possible research direction for these problems, and looks forward to the prospect of modular organization of gene regulatory network

Copyright

© 2017, the Authors. Published by Atlantis Press.

Open Access

This is an open access article distributed under the CC BY-NC license (http://creativecommons.org/licenses/by-nc/4.0/).

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TY  - CONF
AU  - Ming Zheng
AU  - Mugui Zhuo
AU  - Guixia Liu
PY  - 2017/03
DA  - 2017/03
TI  - Research on Modular Construction of Gene Regulatory Network
BT  - Proceedings of the 2017 7th International Conference on Education, Management, Computer and Society (EMCS 2017)
PB  - Atlantis Press
SP  - 896
EP  - 900
SN  - 2352-538X
UR  - https://doi.org/10.2991/emcs-17.2017.171
DO  - 10.2991/emcs-17.2017.171
ID  - Zheng2017/03
ER  -