The Research Progress of Transforming Growth Factor (TGF - Beta) Gene Regulation and Invasion and Metastasis of Pancreatic Cancer
- DOI
- 10.2991/cmes-15.2015.150How to use a DOI?
- Keywords
- transforming growth factors-; gene expression; pancreatic cancer; invasion and metastasis
- Abstract
Transforming growth factors TGF is a kind of a superfamily of peptides, which have strong sensitivity to cell proliferation differention and transfer, its function and its structure are very complicated, and it is a cell factor which widely exist in multiple cells. There are more and more attention on it in the recent years, especially the relation with the tumor is become a key point. TGF- can inhibit related proteins and gene regulation at the early stages of the tumor ,,so can effect the cell proliferation, but at the late stages the tumor, TGF- can also promote the invasion and matastasis of tumor cells. The important feature of pancreatic cancer is a highly mortality rate. But TGF- have two-direction adjust effect to tumor. This article is mainly to the TGF - beta gene expression and the mechanisms and the invasion and metastasis of pancreatic cancer are reviewed in this paper.
- Copyright
- © 2015, the Authors. Published by Atlantis Press.
- Open Access
- This is an open access article distributed under the CC BY-NC license (http://creativecommons.org/licenses/by-nc/4.0/).
Cite this article
TY - CONF AU - Xiao-jing Gong AU - Guiqing Yang AU - Dongning Sun AU - Lingqin Wan AU - Yi-shan Wang PY - 2015/04 DA - 2015/04 TI - The Research Progress of Transforming Growth Factor (TGF - Beta) Gene Regulation and Invasion and Metastasis of Pancreatic Cancer BT - Proceedings of the 2nd International Conference on Civil, Materials and Environmental Sciences PB - Atlantis Press SP - 537 EP - 541 SN - 2352-5401 UR - https://doi.org/10.2991/cmes-15.2015.150 DO - 10.2991/cmes-15.2015.150 ID - Gong2015/04 ER -