Proceedings of the 2nd International Conference on Biomedical and Biological Engineering 2017 (BBE 2017)

Indirect Spectrophotometric Determination of Acetylcysteine in Pharmaceutical Sample using Fe(III)-Sulfosalicylic Acid System

Authors
Xin-rong WEN, Chang-qing TU
Corresponding Author
Xin-rong WEN
Available Online May 2017.
DOI
https://doi.org/10.2991/bbe-17.2017.75How to use a DOI?
Keywords
Acetylcysteine, Fe (III), Sulfosalicylic acid, Discoloration spectrophotome-try.
Abstract
In acidic medium, Fe (III) can be reduced to Fe (II) by hydrosulfuryl (-SH) in acetylcysteine molecule, and then using sulfosalicylic acid as chromogenic reagent of Fe (III) to determinate the acetylcysteine indirectly by discoloration spectrophotometry.An accurate fast spectrophotometric method for the determination of acetylcysteine by discoloration spectrophotometry using Fe (III)-sulfosalicylic acid system has been established. This proposed method had been successfully applied to determinate of acetylcysteine in real pharmaceutical, and the results agreed well with pharmacopoeial method.
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Proceedings
2nd International Conference on Biomedical and Biological Engineering 2017 (BBE 2017)
Part of series
Advances in Biological Sciences Research
Publication Date
May 2017
ISBN
978-94-6252-362-3
ISSN
2468-5747
DOI
https://doi.org/10.2991/bbe-17.2017.75How to use a DOI?
Open Access
This is an open access article distributed under the CC BY-NC license.

Cite this article

TY  - CONF
AU  - Xin-rong WEN
AU  - Chang-qing TU
PY  - 2017/05
DA  - 2017/05
TI  - Indirect Spectrophotometric Determination of Acetylcysteine in Pharmaceutical Sample using Fe(III)-Sulfosalicylic Acid System
BT  - 2nd International Conference on Biomedical and Biological Engineering 2017 (BBE 2017)
PB  - Atlantis Press
SN  - 2468-5747
UR  - https://doi.org/10.2991/bbe-17.2017.75
DO  - https://doi.org/10.2991/bbe-17.2017.75
ID  - WEN2017/05
ER  -