Indirect Spectrophotometric Determination of Acetylcysteine in Pharmaceutical Sample using Fe(III)-Sulfosalicylic Acid System
Xin-rong WEN, Chang-qing TU
Available Online May 2017.
- https://doi.org/10.2991/bbe-17.2017.75How to use a DOI?
- Acetylcysteine, Fe (III), Sulfosalicylic acid, Discoloration spectrophotome-try.
- In acidic medium, Fe (III) can be reduced to Fe (II) by hydrosulfuryl (-SH) in acetylcysteine molecule, and then using sulfosalicylic acid as chromogenic reagent of Fe (III) to determinate the acetylcysteine indirectly by discoloration spectrophotometry.An accurate fast spectrophotometric method for the determination of acetylcysteine by discoloration spectrophotometry using Fe (III)-sulfosalicylic acid system has been established. This proposed method had been successfully applied to determinate of acetylcysteine in real pharmaceutical, and the results agreed well with pharmacopoeial method.
- Open Access
- This is an open access article distributed under the CC BY-NC license.
Cite this article
TY - CONF AU - Xin-rong WEN AU - Chang-qing TU PY - 2017/05 DA - 2017/05 TI - Indirect Spectrophotometric Determination of Acetylcysteine in Pharmaceutical Sample using Fe(III)-Sulfosalicylic Acid System BT - 2nd International Conference on Biomedical and Biological Engineering 2017 (BBE 2017) PB - Atlantis Press SN - 2468-5747 UR - https://doi.org/10.2991/bbe-17.2017.75 DO - https://doi.org/10.2991/bbe-17.2017.75 ID - WEN2017/05 ER -