Proceedings of the 2016 International Conference on Biomedical and Biological Engineering

Synthesis and Characterization of 3-butyryloxy-16-(β-naphthylmethylene)-5α-androstane-17-one

Authors
Hongqi Li, Qingwei Liu, Jueshu Fang, Yulong Wang
Corresponding Author
Hongqi Li
Available Online July 2016.
DOI
10.2991/bbe-16.2016.17How to use a DOI?
Keywords
Androstane, Ester, Aldol condensation, Synthesis, Characterization.
Abstract

3-Butyryloxy-16-(β-naphthylmethylene)-5α-androstane-17-one, a novel androstanone derivative, was synthesized by aldol condensation between epiandrosterone and β-naphthaldehyde and subsequent esterification reaction. The structure of the new product was characterized by 1H NMR, 13C NMR, IR, UV and mass spectra. The new compound may have potential application as anti-cancer agent and/or 5α-reductase inhibitor.

Copyright
© 2016, the Authors. Published by Atlantis Press.
Open Access
This is an open access article distributed under the CC BY-NC license (http://creativecommons.org/licenses/by-nc/4.0/).

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Volume Title
Proceedings of the 2016 International Conference on Biomedical and Biological Engineering
Series
Advances in Biological Sciences Research
Publication Date
July 2016
ISBN
10.2991/bbe-16.2016.17
ISSN
2468-5747
DOI
10.2991/bbe-16.2016.17How to use a DOI?
Copyright
© 2016, the Authors. Published by Atlantis Press.
Open Access
This is an open access article distributed under the CC BY-NC license (http://creativecommons.org/licenses/by-nc/4.0/).

Cite this article

TY  - CONF
AU  - Hongqi Li
AU  - Qingwei Liu
AU  - Jueshu Fang
AU  - Yulong Wang
PY  - 2016/07
DA  - 2016/07
TI  - Synthesis and Characterization of 3-butyryloxy-16-(β-naphthylmethylene)-5α-androstane-17-one
BT  - Proceedings of the 2016 International Conference on Biomedical and Biological Engineering
PB  - Atlantis Press
SP  - 97
EP  - 101
SN  - 2468-5747
UR  - https://doi.org/10.2991/bbe-16.2016.17
DO  - 10.2991/bbe-16.2016.17
ID  - Li2016/07
ER  -