P.48 Ultrasound-Based Velocity and Acceleration of the Carotid Atheromatous Plaque in Asymptomatic Patients with Moderate and Severe Stenosis
- DOI
- 10.2991/artres.k.201209.060How to use a DOI?
- Keywords
- Plaque; motion; carotid; ultrasound
- Abstract
Purpose: The purpose of this study was to investigate differences in ultrasound-based velocities and accelerations of the carotid atheromatous plaque between asymptomatic patients with moderate and severe stenosis, based on the assumption that plaque motion features are sensitive to cardiovascular health status.
Methods: The dataset used consists of 38 sequences of B-mode images (videos) of carotid atheromatous plaque of asymptomatic patients. Among the examined carotid arteries, 27 had severe stenosis degrees (>70%) and 11 had moderate stenosis degrees (<70%). Plaque motion estimation was based on an adaptive block matching methodology which incorporates Kalman filtering update strategies. Plaque velocity and acceleration were calculated by differentiating displacement and velocity, respectively. The two-tailed t-test was used to assess statistically significant differences.
Results: Figure shows examples of plaque velocity and acceleration waveforms. Radial and longitudinal plaque velocities were similar between moderate and severe cases (0.43 ± 0.15 mm/s and 0.73 ± 0.18 mm/s, respectively, vs. 0.37 ± 0.21 mm/s and 0.65 ± 0.20 mm/s, respectively; p-values 0.35 and 0.27, respectively). Radial and longitudinal plaque accelerations were significantly higher in moderate compared to severe stenosis cases (7.07 ± 4.64 mm/s2 and 10.08 ± 5.22 mm/s2, respectively, vs. 3.17 ± 2.25 mm/s2 and 5.05 ± 2.96 mm/s2, respectively; p-values = 0.00 for both cases). In moderate stenoses, longitudinal velocities, but not accelerations, were significantly higher than radial ones, whereas in severe stenoses, longitudinal velocities and accelerations were significantly higher than radial ones.
Figure(a) Example of ultrasound image of the carotid artery with the atheromatous plaque outlined in white. (b), (c) waveforms of radial and longitudinal velocities, respectively, of the plaque in (a). (d), (e) waveforms of radial and longitudinal accelerations, respectively, of the plaque in (a).
Conclusion: Ultrasound-based velocities and accelerations can characterise biomechanical phenomena of the carotid plaque. Accelerations can differentiate between moderate and severe plaque.
- Copyright
- © 2020 Association for Research into Arterial Structure and Physiology. Publishing services by Atlantis Press International B.V.
- Open Access
- This is an open access article distributed under the CC BY-NC 4.0 license (http://creativecommons.org/licenses/by-nc/4.0/).
Cite this article
TY - JOUR AU - Kalliopi Dalakleidi AU - Spyretta Golemati AU - Aimilia Gastounioti AU - Christos Liapis AU - Konstantina Nikita PY - 2020 DA - 2020/12/31 TI - P.48 Ultrasound-Based Velocity and Acceleration of the Carotid Atheromatous Plaque in Asymptomatic Patients with Moderate and Severe Stenosis JO - Artery Research SP - S71 EP - S71 VL - 26 IS - Supplement 1 SN - 1876-4401 UR - https://doi.org/10.2991/artres.k.201209.060 DO - 10.2991/artres.k.201209.060 ID - Dalakleidi2020 ER -