Artery Research

Volume 26, Issue Supplement 1, December 2020, Pages S71 - S71

P.48 Ultrasound-Based Velocity and Acceleration of the Carotid Atheromatous Plaque in Asymptomatic Patients with Moderate and Severe Stenosis

Authors
Kalliopi Dalakleidi1, *, Spyretta Golemati2, Aimilia Gastounioti3, Christos Liapis4, Konstantina Nikita1
1Biomedical Simulations and Imaging Lab., School of Electrical and Computer Engineering, National Technical University of Athens
2Medical School, National and Kapodistrian University of Athens
3Department of Radiology, University of Pennsylvania
4Attikon University General Hospital, Medical School, National and Kapodistrian University of Athens
*Corresponding author. Email: kdalakleidi@biosim.ntua.gr
Corresponding Author
Kalliopi Dalakleidi
Available Online 31 December 2020.
DOI
10.2991/artres.k.201209.060How to use a DOI?
Keywords
Plaque; motion; carotid; ultrasound
Abstract

Purpose: The purpose of this study was to investigate differences in ultrasound-based velocities and accelerations of the carotid atheromatous plaque between asymptomatic patients with moderate and severe stenosis, based on the assumption that plaque motion features are sensitive to cardiovascular health status.

Methods: The dataset used consists of 38 sequences of B-mode images (videos) of carotid atheromatous plaque of asymptomatic patients. Among the examined carotid arteries, 27 had severe stenosis degrees (>70%) and 11 had moderate stenosis degrees (<70%). Plaque motion estimation was based on an adaptive block matching methodology which incorporates Kalman filtering update strategies. Plaque velocity and acceleration were calculated by differentiating displacement and velocity, respectively. The two-tailed t-test was used to assess statistically significant differences.

Results: Figure shows examples of plaque velocity and acceleration waveforms. Radial and longitudinal plaque velocities were similar between moderate and severe cases (0.43 ± 0.15 mm/s and 0.73 ± 0.18 mm/s, respectively, vs. 0.37 ± 0.21 mm/s and 0.65 ± 0.20 mm/s, respectively; p-values 0.35 and 0.27, respectively). Radial and longitudinal plaque accelerations were significantly higher in moderate compared to severe stenosis cases (7.07 ± 4.64 mm/s2 and 10.08 ± 5.22 mm/s2, respectively, vs. 3.17 ± 2.25 mm/s2 and 5.05 ± 2.96 mm/s2, respectively; p-values = 0.00 for both cases). In moderate stenoses, longitudinal velocities, but not accelerations, were significantly higher than radial ones, whereas in severe stenoses, longitudinal velocities and accelerations were significantly higher than radial ones.

Figure

(a) Example of ultrasound image of the carotid artery with the atheromatous plaque outlined in white. (b), (c) waveforms of radial and longitudinal velocities, respectively, of the plaque in (a). (d), (e) waveforms of radial and longitudinal accelerations, respectively, of the plaque in (a).

Conclusion: Ultrasound-based velocities and accelerations can characterise biomechanical phenomena of the carotid plaque. Accelerations can differentiate between moderate and severe plaque.

Copyright
© 2020 Association for Research into Arterial Structure and Physiology. Publishing services by Atlantis Press International B.V.
Open Access
This is an open access article distributed under the CC BY-NC 4.0 license (http://creativecommons.org/licenses/by-nc/4.0/).

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Journal
Artery Research
Volume-Issue
26 - Supplement 1
Pages
S71 - S71
Publication Date
2020/12/31
ISSN (Online)
1876-4401
ISSN (Print)
1872-9312
DOI
10.2991/artres.k.201209.060How to use a DOI?
Copyright
© 2020 Association for Research into Arterial Structure and Physiology. Publishing services by Atlantis Press International B.V.
Open Access
This is an open access article distributed under the CC BY-NC 4.0 license (http://creativecommons.org/licenses/by-nc/4.0/).

Cite this article

TY  - JOUR
AU  - Kalliopi Dalakleidi
AU  - Spyretta Golemati
AU  - Aimilia Gastounioti
AU  - Christos Liapis
AU  - Konstantina Nikita
PY  - 2020
DA  - 2020/12/31
TI  - P.48 Ultrasound-Based Velocity and Acceleration of the Carotid Atheromatous Plaque in Asymptomatic Patients with Moderate and Severe Stenosis
JO  - Artery Research
SP  - S71
EP  - S71
VL  - 26
IS  - Supplement 1
SN  - 1876-4401
UR  - https://doi.org/10.2991/artres.k.201209.060
DO  - 10.2991/artres.k.201209.060
ID  - Dalakleidi2020
ER  -