P1.06 CARDIO-ANKLE VASCULAR INDEX (CAVI) IS AN INDEPENDENT PREDICTOR OF DEATH IN MAINTENANCE HEMODIALYSIS PATIENTS

Shirai Kohji; Kono Takashi; Nagayama Daiji; Saiki Atsuhito; Utino Junji; Tuchiya Shoji; Yoshida Toyohiko

doi:10.1016/j.artres.2013.10.037

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Volume 7, Issue 3-4, September 2013, Pages 112 - 112

P1.06 CARDIO-ANKLE VASCULAR INDEX (CAVI) IS AN INDEPENDENT PREDICTOR OF DEATH IN MAINTENANCE HEMODIALYSIS PATIENTS

Authors

Shirai Kohji¹, Kono Takashi¹, Nagayama Daiji², Saiki Atsuhito², Utino Junji¹, Tuchiya Shoji¹, Yoshida Toyohiko¹

¹Mihama Hospital, Chiba, Japan

²Internal Medicine, Sakura Hospital, Toho-Univ, Chiba, Japan

Available Online 11 November 2013.

DOI: 10.1016/j.artres.2013.10.037 How to use a DOI?
Abstract: Objects: The purpose of this study was to calculate robust quantitative estimates of the predictive value of cardio-ankle vascular index, (CAVI) for future all-cause mortality in hemodialysis patients.

Subjects and methods: A total of 163 hemodialysis patients (102 males and 61 females, mean age 60±11 years), who had the examination of CAVI between 2004 and 2005 at Mihama Narita Clinic, Chiba, Japan, were included and followed up for 80 months. Those had diabetes mellitus (27.0%), hypertension (77.3%) or/and dyslipidemia (36.8%). CAVI was measured using Vasela1500 (Fukuda Denshi. Co.LTD).

Results: Among 163 hemodialysis patients, 51 deaths were observed in 6.5 years. Causes of death were heart disease (37.3%), brain stroke (19.6%), infection (17.6%), suffocation (3.9%) and others. In subjects with death, higher CAVI (9.3±1.8 vs. 8.3±1.2), mean age (65±12 vs. 57±10 years) and prevalence of diabetic nephropathy (43.1 vs. 19.6%) were observed.

COX proportional-hazards regression analysis of the association between death and clinical variables showed that high CAVI (≥10) independently increased the risk of death with OR of 2.605 (95% CI 1.321–5.141, P=0.006). OR of Diabetic nephropathy was 2.027(95%CI 1.102–3.727, P=0.023) and OR of elderly (≥65 years) was 3,152, (95%CI 1.758–5.649, P<0.0001).

Kaplan-Meier curves for cumulative survival in hemodialysis patients stratified by severity of CAVI(8>, 9>,10>, 10<) showed that the survival rates on the patients with higher CAVI groups were significantly low (P=0.002, Log-rank test).

Conclusion: CAVI is an independent predictor of death in hemodialysis patients.
Open Access: This is an open access article distributed under the CC BY-NC license.

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Journal: Artery Research
Volume-Issue: 7 - 3-4
Pages: 112 - 112
Publication Date: 2013/11/11
ISSN (Online): 1876-4401
ISSN (Print): 1872-9312
DOI: 10.1016/j.artres.2013.10.037 How to use a DOI?
Open Access: This is an open access article distributed under the CC BY-NC license.

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ris enw bib

TY  - JOUR
AU  - Shirai Kohji
AU  - Kono Takashi
AU  - Nagayama Daiji
AU  - Saiki Atsuhito
AU  - Utino Junji
AU  - Tuchiya Shoji
AU  - Yoshida Toyohiko
PY  - 2013
DA  - 2013/11/11
TI  - P1.06 CARDIO-ANKLE VASCULAR INDEX (CAVI) IS AN INDEPENDENT PREDICTOR OF DEATH IN MAINTENANCE HEMODIALYSIS PATIENTS
JO  - Artery Research
SP  - 112
EP  - 112
VL  - 7
IS  - 3-4
SN  - 1876-4401
UR  - https://doi.org/10.1016/j.artres.2013.10.037
DO  - 10.1016/j.artres.2013.10.037
ID  - Kohji2013
ER  -

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