Artery Research

Volume 7, Issue 3-4, September 2013, Pages 112 - 112

P1.06 CARDIO-ANKLE VASCULAR INDEX (CAVI) IS AN INDEPENDENT PREDICTOR OF DEATH IN MAINTENANCE HEMODIALYSIS PATIENTS

Authors
Shirai Kohji1, Kono Takashi1, Nagayama Daiji2, Saiki Atsuhito2, Utino Junji1, Tuchiya Shoji1, Yoshida Toyohiko1
1Mihama Hospital, Chiba, Japan
2Internal Medicine, Sakura Hospital, Toho-Univ, Chiba, Japan
Available Online 11 November 2013.
DOI
10.1016/j.artres.2013.10.037How to use a DOI?
Abstract

Objects: The purpose of this study was to calculate robust quantitative estimates of the predictive value of cardio-ankle vascular index, (CAVI) for future all-cause mortality in hemodialysis patients.

Subjects and methods: A total of 163 hemodialysis patients (102 males and 61 females, mean age 60±11 years), who had the examination of CAVI between 2004 and 2005 at Mihama Narita Clinic, Chiba, Japan, were included and followed up for 80 months. Those had diabetes mellitus (27.0%), hypertension (77.3%) or/and dyslipidemia (36.8%). CAVI was measured using Vasela1500 (Fukuda Denshi. Co.LTD).

Results: Among 163 hemodialysis patients, 51 deaths were observed in 6.5 years. Causes of death were heart disease (37.3%), brain stroke (19.6%), infection (17.6%), suffocation (3.9%) and others. In subjects with death, higher CAVI (9.3±1.8 vs. 8.3±1.2), mean age (65±12 vs. 57±10 years) and prevalence of diabetic nephropathy (43.1 vs. 19.6%) were observed.

COX proportional-hazards regression analysis of the association between death and clinical variables showed that high CAVI (≥10) independently increased the risk of death with OR of 2.605 (95% CI 1.321–5.141, P=0.006). OR of Diabetic nephropathy was 2.027(95%CI 1.102–3.727, P=0.023) and OR of elderly (≥65 years) was 3,152, (95%CI 1.758–5.649, P<0.0001).

Kaplan-Meier curves for cumulative survival in hemodialysis patients stratified by severity of CAVI(8>, 9>,10>, 10<) showed that the survival rates on the patients with higher CAVI groups were significantly low (P=0.002, Log-rank test).

Conclusion: CAVI is an independent predictor of death in hemodialysis patients.

Open Access
This is an open access article distributed under the CC BY-NC license.

Journal
Artery Research
Volume-Issue
7 - 3-4
Pages
112 - 112
Publication Date
2013/11/11
ISSN (Online)
1876-4401
ISSN (Print)
1872-9312
DOI
10.1016/j.artres.2013.10.037How to use a DOI?
Open Access
This is an open access article distributed under the CC BY-NC license.

Cite this article

TY  - JOUR
AU  - Shirai Kohji
AU  - Kono Takashi
AU  - Nagayama Daiji
AU  - Saiki Atsuhito
AU  - Utino Junji
AU  - Tuchiya Shoji
AU  - Yoshida Toyohiko
PY  - 2013
DA  - 2013/11/11
TI  - P1.06 CARDIO-ANKLE VASCULAR INDEX (CAVI) IS AN INDEPENDENT PREDICTOR OF DEATH IN MAINTENANCE HEMODIALYSIS PATIENTS
JO  - Artery Research
SP  - 112
EP  - 112
VL  - 7
IS  - 3-4
SN  - 1876-4401
UR  - https://doi.org/10.1016/j.artres.2013.10.037
DO  - 10.1016/j.artres.2013.10.037
ID  - Kohji2013
ER  -