Artery Research

Volume 26, Issue 1, March 2020, Pages 1 - 4

Pharmacological Management of Hypertension Guided by Central or Peripheral Blood Pressure Measurement: Comparison of Two Strategies on the Incidence of Intermediate Outcome

Authors
Weimar Kunz Sebba Barroso1, 2, 3, *, Sayuri Inuzuka1, 2, Gilberto Campos Guimarães1, 2, Robson Pierre Pacífico3, Victoria Alves Melo3, Luiz Fernando Oliveira3, Eduarda Silva3, Gustavo Ribeiro Mesquita3, Deborah Silva Cintra Valle3, Priscila Valverde Vitorino4, Ana Luiza Lima Sousa1, 2, Paulo César Brandão Veiga Jardim1, 2, Antonio Coca5
1Hypertension League, Cardiology Department, Federal University Goiás, Goiânia, Goiás, Brazil
2Health Sciences Post-Graduation Program, Federal University Goiás, Goiânia, Goiás, Brazil
3Medical School, Graduation Program, Federal University Goiás, Goiânia, Goiás, Brazil
4Research Department, Pontifical Catholic University, Goiânia, Goiás, Brazil
5Hypertension Unit, Barcelona University, Barcelona, Spain
*Corresponding author. Email: sebbabarroso@gmail.com
Corresponding Author
Weimar Kunz Sebba Barroso
Received 31 December 2019, Accepted 3 January 2020, Available Online 23 January 2020.
DOI
https://doi.org/10.2991/artres.k.200104.001How to use a DOI?
Keywords
Central blood pressure, hypertension, risk factors, evidence-based practice
Abstract

Background: Central blood pressure values and arterial stiffness have demonstrated to be a useful tool to stratify cardiovascular risk and also as a biomarker. A question that is still unanswered is if hypertension treatment guided by central blood pressure parameters will be even better to promote cardiovascular protection than peripheral one.

Methods: With this proposition we have designed an open prospective multicentric randomized protocol to compare central (G1) and peripheral (G2) blood pressure targets during 1 year follow-up concerning target organ damage (carotid intima media thickness, left ventricular hypertrophy, microalbuminuria and pulse wave velocity). OMRON 1100 will be used to access peripheral and Mobil O’Graph to access central blood pressure and pulse wave velocity, TOSHIBA Xsario with longitudinal linear transdutor 7.5 MHz bidimensional mode B to access carotid and left ventricular parameters.

Expected Results: This paper aims to describe methodological aspects concerning this research and we expect to find results to answer some open questions about hypertension treatment and cardiovascular protection.

Copyright
© 2020 Association for Research into Arterial Structure and Physiology. Publishing services by Atlantis Press International B.V.
Open Access
This is an open access article distributed under the CC BY-NC 4.0 license (http://creativecommons.org/licenses/by-nc/4.0/).

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Journal
Artery Research
Volume-Issue
26 - 1
Pages
1 - 4
Publication Date
2020/01
ISSN (Online)
1876-4401
ISSN (Print)
1872-9312
DOI
https://doi.org/10.2991/artres.k.200104.001How to use a DOI?
Copyright
© 2020 Association for Research into Arterial Structure and Physiology. Publishing services by Atlantis Press International B.V.
Open Access
This is an open access article distributed under the CC BY-NC 4.0 license (http://creativecommons.org/licenses/by-nc/4.0/).

Cite this article

TY  - JOUR
AU  - Weimar Kunz Sebba Barroso
AU  - Sayuri Inuzuka
AU  - Gilberto Campos Guimarães
AU  - Robson Pierre Pacífico
AU  - Victoria Alves Melo
AU  - Luiz Fernando Oliveira
AU  - Eduarda Silva
AU  - Gustavo Ribeiro Mesquita
AU  - Deborah Silva Cintra Valle
AU  - Priscila Valverde Vitorino
AU  - Ana Luiza Lima Sousa
AU  - Paulo César Brandão Veiga Jardim
AU  - Antonio Coca
PY  - 2020
DA  - 2020/01
TI  - Pharmacological Management of Hypertension Guided by Central or Peripheral Blood Pressure Measurement: Comparison of Two Strategies on the Incidence of Intermediate Outcome
JO  - Artery Research
SP  - 1
EP  - 4
VL  - 26
IS  - 1
SN  - 1876-4401
UR  - https://doi.org/10.2991/artres.k.200104.001
DO  - https://doi.org/10.2991/artres.k.200104.001
ID  - Barroso2020
ER  -