Artery Research

Volume 12, Issue C, December 2015, Pages 41 - 41

2.2 RE-REFLECTION OF BACKWARD PROPAGATING WAVES LEADS TO AMPLIFICATION OF THE FORWARD PRESSURE WAVE IN WAVE SEPARATION ANALYSIS

Authors
Patrick Segers*, Liesbeth Taelman, Joris Degroote, Jan Vierendeels
Ghent University, Gent, Belgium
Available Online 23 November 2015.
DOI
10.1016/j.artres.2015.10.009How to use a DOI?
Abstract

Introduction: In wave separation analysis, the pressure wave is decomposed into a single forward and backward component, which actually compounds all forward and backward propagating waves. We hypothesize that, in particular in presence of early reflections as in aortic coarctation, re-reflection of backward propagating waves at the ventricular-arterial interface amplifies the forward wave component.

Methods: We set up a 3D fluid-structure interaction model of the aorta based on MRI scans of a healthy volunteer. With the healthy model as reference, we introduced a 25 mm narrowing section in the descending thoracic aorta to model an aortic coarctation, with coarctation index (CI) 0.65 and 0.5. Inflow and outflow boundary conditions were kept constant to allow studying the isolated effect of the coarctation. Aortic root pressure and flow waveforms were extracted and subjected to wave intensity and wave separation analysis.

Results: The presence of the coarctation increased systolic pressure by 10 mmHg and 41 mmHg for CI 0.65 and 0.5, respectively. Wave separation analysis indicated that this increase in blood pressure was about equally due to an increase in the amplitude of both the forward and backward pressure wave. Wave intensity analysis - though only after separating into forward and backward wave intensity - revealed that the amplification of the forward pressure wave is caused by re-reflection of backward waves at the level of the aortic valve.

Conclusion: We conclude that wave separation analysis might overestimate the incident pressure wave component because of re-reflection of backward waves at the aortic valve.

Open Access
This is an open access article distributed under the CC BY-NC license.

Journal
Artery Research
Volume-Issue
12 - C
Pages
41 - 41
Publication Date
2015/11/23
ISSN (Online)
1876-4401
ISSN (Print)
1872-9312
DOI
10.1016/j.artres.2015.10.009How to use a DOI?
Open Access
This is an open access article distributed under the CC BY-NC license.

Cite this article

TY  - JOUR
AU  - Patrick Segers*
AU  - Liesbeth Taelman
AU  - Joris Degroote
AU  - Jan Vierendeels
PY  - 2015
DA  - 2015/11/23
TI  - 2.2 RE-REFLECTION OF BACKWARD PROPAGATING WAVES LEADS TO AMPLIFICATION OF THE FORWARD PRESSURE WAVE IN WAVE SEPARATION ANALYSIS
JO  - Artery Research
SP  - 41
EP  - 41
VL  - 12
IS  - C
SN  - 1876-4401
UR  - https://doi.org/10.1016/j.artres.2015.10.009
DO  - 10.1016/j.artres.2015.10.009
ID  - Segers*2015
ER  -